Therapeutic strategies to ameliorate neuronal damage in epilepsy by regulating oxidative stress, mitochondrial dysfunction, and neuroinflammation

S Madireddy, S Madireddy - Brain sciences, 2023 - mdpi.com
Epilepsy is a central nervous system disorder involving spontaneous and recurring seizures
that affects 50 million individuals globally. Because approximately one-third of patients with …

[HTML][HTML] Neurodevelopmental disorders: Metallomics studies for the identification of potential biomarkers associated to diagnosis and treatment

C Scassellati, C Bonvicini, L Benussi, R Ghidoni… - Journal of Trace …, 2020 - Elsevier
Background Diagnosis and treatment of complex diseases such as Neurodevelopmental
Disorders (NDDs) can be resolved through the identification of biomarkers. Metallomics …

Whole blood trace element and toxic metal concentration in dogs with idiopathic epilepsy and healthy dogs: a case-control study

S Rosendahl, J Anturaniemi… - Frontiers in Veterinary …, 2023 - frontiersin.org
Background Idiopathic epilepsy (IE) is the most common neurological disease in dogs.
Multiple genes and environmental factors interact to cause clinical signs, although the …

The association of oxidative stress biomarkers with type 2 diabetes mellitus: A systematic review and meta‐analysis

S Banik, A Ghosh - Health science reports, 2021 - Wiley Online Library
Abstract Background and Aims Oxidative stress plays a major role in the development of
type 2 diabetes mellitus (T2DM). However, there were controversial outcomes in the …

Role of vitamins in epilepsy

MT Yang, IC Chou, HS Wang - Epilepsy & Behavior, 2023 - Elsevier
Epilepsy is a chronic neurological disorder that presents as recurrent, unprovoked seizures.
Pharmacotherapy is the main treatment for epilepsy, but at least 30% of patients with …

[HTML][HTML] Circulating malondialdehyde level in patients with epilepsy: A meta-analysis

H Sun, J Li, B Maimaiti, J Liu, Z Li, Y Cheng… - … : European Journal of …, 2022 - Elsevier
Purpose Malondialdehyde (MDA) is an oxidative stress marker that determines the impact of
oxidation on MDA levels in patients with epilepsy (PWE) and healthy controls. Methods A …

The mechanism of cuproptosis in Parkinson's disease

M Huang, Y Zhang, X Liu - Ageing Research Reviews, 2024 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease with an increased morbidity. The
pathogenesis PD has not been fully elucidated, and whatever mechanism is involved, it …

Functional nutrients for epilepsy

JE Kim, KO Cho - Nutrients, 2019 - mdpi.com
Epilepsy is a common neurological disorder of which seizures are a core symptom.
Approximately one third of epileptic patients are resistant to antiepileptic drugs and therefore …

The changes of serum zinc, copper, and selenium levels in epileptic patients: a systematic review and meta-analysis

W Jia, Y Song, L Yang, J Kong, T Boczek… - Expert Review of …, 2020 - Taylor & Francis
Introduction It is widely accepted that trace elements have been implicated in various
metabolic processes. Valproic acid (VPA) is a remarkably safe and effective antiepileptic …

Phyto-Mediated Synthesis of Copper Oxide Nanoparticles: an Investigation of Antioxidant, Antimicrobial, Anti-Inflammatory, and Protective Neuropsychiatric Potential

N Bhardwaj, S Puri, A Kumari, A Chauhan, A Kumar - BioNanoScience, 2024 - Springer
Nanotechnology, particularly green nanotechnology, focuses on utilizing natural materials,
especially plant-based sources rich in phytoconstituents, which have the potential to combat …