Freeze-drying has been considered as a good technique to improve the long-term stability of
colloidal nanoparticles. The poor stability in an aqueous medium of these systems forms a …

Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Polymeric drug-loaded nanoparticles have been extensively studied in the field of drug
delivery. Biodistribution depends on the physicochemical properties of particles, especially …

Background: Synthetic nanoparticles are emerging as versatile tools in biomedical
applications, particularly in the area of biomedical imaging. Nanoparticles 1–100 nm in …

Purpose To evaluate the pharmacological activity of insulin-loaded alginate/chitosan
nanoparticles following oral dosage in diabetic rats. Methods Nanoparticles were prepared …

Diabetic cases have increased rapidly in recent years throughout the world. Currently, for
type-1 diabetes mellitus (T1DM), multiple daily insulin (MDI) injections is the most popular …

The present study was to demonstrate the effects of goblet cell-targeting nanoparticles on
the oral absorption of insulin in vitro, ex vivo and in vivo, and identify the targeting …

This paper reviews the major factors that are closely involved in peptide and protein
degradation during the preparation of biodegradable nano-and microparticles. The various …

Therapeutic application of nucleic acids requires their encapsulation in nanosized carriers
that enable safe and efficient intracellular delivery. Before the desired site of action is …

Alginate nanoparticles were prepared from dilute alginate sol by inducing a pre-gel with
calcium counter ions, followed by polyelectrolyte complex coating with chitosan. Particles in …