Structural basis of potential inhibitors targeting SARS-CoV-2 main protease
The Coronavirus disease-19 (COVID-19) pandemic is still devastating the world causing
significant social, economic, and political chaos. Corresponding to the absence of globally …
significant social, economic, and political chaos. Corresponding to the absence of globally …
Seaweed phenolics: From extraction to applications
Seaweeds have attracted high interest in recent years due to their chemical and bioactive
properties to find new molecules with valuable applications for humankind. Phenolic …
properties to find new molecules with valuable applications for humankind. Phenolic …
COCONUT online: collection of open natural products database
Natural products (NPs) are small molecules produced by living organisms with potential
applications in pharmacology and other industries as many of them are bioactive. This …
applications in pharmacology and other industries as many of them are bioactive. This …
An updated review of computer‐aided drug design and its application to COVID‐19
The recent outbreak of the deadly coronavirus disease 19 (COVID‐19) pandemic poses
serious health concerns around the world. The lack of approved drugs or vaccines continues …
serious health concerns around the world. The lack of approved drugs or vaccines continues …
[HTML][HTML] Molecular docking, validation, dynamics simulations, and pharmacokinetic prediction of natural compounds against the SARS-CoV-2 main-protease
C Shivanika, D Kumar, V Ragunathan… - … structure & dynamics, 2020 - ncbi.nlm.nih.gov
The study aims to evaluate the potency of two hundred natural antiviral phytocompounds
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
against the active site of the Severe Acquired Respiratory Syndrome-Coronavirus− 2 (SARS …
Essential oils as antiviral agents, potential of essential oils to treat SARS-CoV-2 infection: an in-silico investigation
JKR Da Silva, PLB Figueiredo, KG Byler… - International journal of …, 2020 - mdpi.com
Essential oils have shown promise as antiviral agents against several pathogenic viruses. In
this work we hypothesized that essential oil components may interact with key protein …
this work we hypothesized that essential oil components may interact with key protein …
Potential SARS-CoV-2 main protease inhibitors
R Banerjee, L Perera, LMV Tillekeratne - Drug Discovery Today, 2021 - Elsevier
Highlights•The SARS-CoV-2 main protease is a prime drug target.•Coronavirus main
proteases share a structurally conserved substrate-binding region.•The structure and …
proteases share a structurally conserved substrate-binding region.•The structure and …
[HTML][HTML] Phytochemicals containing biologically active polyphenols as an effective agent against Covid-19-inducing coronavirus
The outbreak of Covid-19 disease caused by SARS-CoV-19, along with the lack of targeted
medicaments and vaccines, forced the scientific world to search for new antiviral …
medicaments and vaccines, forced the scientific world to search for new antiviral …
Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …
Natural products' role against COVID-19
A da Silva Antonio, LSM Wiedemann… - RSC advances, 2020 - pubs.rsc.org
COVID-19 is a viral disease caused by a new severe acute respiratory syndrome (SARS-
CoV-2), which has quickly resulted in a pandemic. As a great threat to global public health …
CoV-2), which has quickly resulted in a pandemic. As a great threat to global public health …