[HTML][HTML] Sarcopenia in the older adult with cancer

GR Williams, RF Dunne, S Giri… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The term sarcopenia, derived from the Greek words sarx for flesh and penia for loss, was first
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …

Myosteatosis and prognosis in cancer: systematic review and meta-analysis

GFP Aleixo, SS Shachar, KA Nyrop, HB Muss… - Critical reviews in …, 2020 - Elsevier
Background The evidence that body composition parameters influence multiple cancer
outcomes is rapidly expanding. Excess adiposity deposits in muscle tissue, termed …

[HTML][HTML] Sarcopenic obesity: hidden muscle wasting and its impact for survival and complications of cancer therapy

VE Baracos, L Arribas - Annals of Oncology, 2018 - Elsevier
Body composition, defined as the proportions and distribution of lean and fat tissues in the
human body, is an emergent theme in clinical oncology. Severe muscle depletion …

[HTML][HTML] Sarcopenia associated with chemotherapy and targeted agents for cancer therapy

MP Davis, R Panikkar - Annals of palliative medicine, 2019 - apm.amegroups.org
Clinicians often believe that cachexia is caused by cancer and anorexia as a toxicity of
chemotherapy or targeted anti-cancer agents. It is now recognized that chemotherapy and …

Low skeletal muscle mass is a predictive factor for chemotherapy dose-limiting toxicity in patients with locally advanced head and neck cancer

AW Wendrich, JE Swartz, SI Bril, I Wegner, A de Graeff… - Oral oncology, 2017 - Elsevier
Objectives Low skeletal muscle mass (SMM) or sarcopenia is emerging as an adverse
prognostic factor for chemotherapy dose-limiting toxicity (CLDT) and survival in cancer …

Impact of sarcopenia in patients with advanced non–small cell lung cancer treated with PD-1 inhibitors: A preliminary retrospective study

T Shiroyama, I Nagatomo, S Koyama, H Hirata… - Scientific reports, 2019 - nature.com
The aim of this study was to investigate the clinical impact of sarcopenia on the efficacy of
programmed death (PD)-1 inhibitors. We retrospectively reviewed the medical records of all …

A machine learning algorithm to estimate sarcopenia on abdominal CT

JE Burns, J Yao, D Chalhoub, JJ Chen, RM Summers - Academic radiology, 2020 - Elsevier
Rationale and Objectives To assess whether a fully-automated deep learning system can
accurately detect and analyze truncal musculature at multiple lumbar vertebral levels and …

Phenotypic features of cancer cachexia‐related loss of skeletal muscle mass and function: lessons from human and animal studies

A Martin, D Freyssenet - Journal of cachexia, sarcopenia and …, 2021 - Wiley Online Library
Cancer cachexia is a complex multi‐organ catabolic syndrome that reduces mobility,
increases fatigue, decreases the efficiency of therapeutic strategies, diminishes the quality of …

Prevalence of sarcopenia in patients with solid tumors: a meta‐analysis based on 81,814 patients

A Surov, A Wienke - Journal of Parenteral and Enteral Nutrition, 2022 - Wiley Online Library
Background The purpose of the present meta‐analysis was to analyze the prevalence of
sarcopenia on staging computed tomography (CT) in patients with different malignant solid …

Low muscle attenuation is a prognostic factor for survival in metastatic breast cancer patients treated with first line palliative chemotherapy

HN Rier, A Jager, S Sleijfer, J van Rosmalen… - The Breast, 2017 - Elsevier
Background Low muscle mass (LMM) and low muscle attenuation (LMA) reflect low muscle
quantity and low muscle quality, respectively. Both are associated with a poor outcome in …