How cortical circuits implement cortical computations: mouse visual cortex as a model

CM Niell, M Scanziani - Annual Review of Neuroscience, 2021 - annualreviews.org
The mouse, as a model organism to study the brain, gives us unprecedented experimental
access to the mammalian cerebral cortex. By determining the cortex's cellular composition …

From progenitors to progeny: shaping striatal circuit development and function

R Knowles, N Dehorter, T Ellender - Journal of Neuroscience, 2021 - Soc Neuroscience
Understanding how neurons of the striatum are formed and integrate into complex synaptic
circuits is essential to provide insight into striatal function in health and disease. In this …

A comprehensive excitatory input map of the striatum reveals novel functional organization

BJ Hunnicutt, BC Jongbloets, WT Birdsong, KJ Gertz… - elife, 2016 - elifesciences.org
The striatum integrates excitatory inputs from the cortex and the thalamus to control diverse
functions. Although the striatum is thought to consist of sensorimotor, associative and limbic …

Primate homologs of mouse cortico-striatal circuits

JH Balsters, V Zerbi, J Sallet, N Wenderoth, RB Mars - Elife, 2020 - elifesciences.org
With the increasing necessity of animal models in biomedical research, there is a vital need
to harmonise findings across species by establishing similarities and differences in rodent …

Ongoing movement controls sensory integration in the dorsolateral striatum

R de la Torre-Martinez, M Ketzef… - Nature Communications, 2023 - nature.com
The dorsolateral striatum (DLS) receives excitatory inputs from both sensory and motor
cortical regions. In the neocortex, sensory responses are affected by motor activity, however …

Parkinsonism-related β oscillations in the primate basal ganglia networks–recent advances and clinical implications

M Deffains, H Bergman - Parkinsonism & related disorders, 2019 - Elsevier
Today, the basal ganglia (BG) network can be viewed as a three-layer neural network in
which the striatum and the subthalamic nucleus (STN) are the two BG input structures and …

Dopamine axons in dorsal striatum encode contralateral visual stimuli and choices

MM Moss, P Zatka-Haas, KD Harris… - Journal of …, 2021 - Soc Neuroscience
The striatum plays critical roles in visually-guided decision-making and receives dense
axonal projections from midbrain dopamine neurons. However, the roles of striatal …

Temporal regularities shape perceptual decisions and striatal dopamine signals

M Fritsche, A Majumdar, L Strickland… - Nature …, 2024 - nature.com
Perceptual decisions should depend on sensory evidence. However, such decisions are
also influenced by past choices and outcomes. These choice history biases may reflect …

Volitional modulation of primary visual cortex activity requires the basal ganglia

RM Neely, AC Koralek, VR Athalye, RM Costa… - Neuron, 2018 - cell.com
Animals acquire behaviors through instrumental conditioning. Brain-machine interfaces
have used instrumental conditioning to reinforce patterns of neural activity directly …

Distinct patterns of connectivity between brain regions underlie the intra-modal and cross-modal value-driven modulations of the visual cortex

JE Antono, S Dang, R Auksztulewicz… - Journal of …, 2023 - Soc Neuroscience
Past reward associations may be signaled from different sensory modalities; however, it
remains unclear how different types of reward-associated stimuli modulate sensory …