Revisiting microbial keratinases: next generation proteases for sustainable biotechnology

R Gupta, R Sharma, QK Beg - Critical reviews in biotechnology, 2013 - Taylor & Francis
Keratinases are special proteases which attack the highly recalcitrant keratin substrates.
They stand apart from the conventional proteases due to their broad substrate specificity …

The tale of a versatile enzyme: molecular insights into keratinase for its industrial dissemination

C Su, JS Gong, J Qin, H Li, H Li, ZH Xu, JS Shi - Biotechnology Advances, 2020 - Elsevier
Keratinases are unique among proteolytic enzymes for their ability to degrade recalcitrant
insoluble proteins, and they are of critical importance in keratin waste management. Over …

Challenges and opportunities in identifying and characterising keratinases for value-added peptide production

JP De Oliveira Martinez, G Cai, M Nachtschatt… - Catalysts, 2020 - mdpi.com
Keratins are important structural proteins produced by mammals, birds and reptiles. Keratins
usually act as a protective barrier or a mechanical support. Millions of tonnes of keratin …

Genome and secretome analyses provide insights into keratin decomposition by novel proteases from the non-pathogenic fungus Onygena corvina

Y Huang, PK Busk, FA Herbst, L Lange - Applied microbiology and …, 2015 - Springer
Poultry processing plants and slaughterhouses produce huge quantities of feathers and
hair/bristle waste annually. These keratinaceous wastes are highly resistant to degradation …

Combining pro-peptide engineering and multisite saturation mutagenesis to improve the catalytic potential of keratinase

C Su, JS Gong, YX Sun, J Qin, S Zhai, H Li… - ACS Synthetic …, 2019 - ACS Publications
Keratinases are becoming biotechnologically important since they have shown potential in
hydrolysis of recalcitrant keratins with highly rigid and strongly cross-linked structures …

Engineered pro‐peptide enhances the catalytic activity of keratinase to improve the conversion ability of feather waste

Z Peng, J Zhang, Y Song, R Guo… - Biotechnology and …, 2021 - Wiley Online Library
Keratinase is an attractive industrial enzyme that can specifically catalyze keratin waste to
obtain value‐added products. A challenge to the application of keratinase is improving …

Current Progress and Biotechnological Applications of Microbial Keratinases.

I Gahatraj, A Borah, P Pandey… - Journal of Pure & …, 2023 - search.ebscohost.com
Keratin is a fibrous and recalcitrant protein found in feathers, nails, horns, hooves, and the
epidermis of the skin. The presence of the high degree of disulfide bonds, hydrogen bonds …

Improvement of expression level of keratinase Sfp2 from Streptomyces fradiae by site-directed mutagenesis of its N-terminal pro-sequence

J Li, D Chen, Z Yu, L Zhao, R Zhang - Biotechnology letters, 2013 - Springer
The keratinase Sfp2, produced by Streptomyces fradiae var. k11, is a serine alkaline
protease first synthesized as pre-pro-mature precursor, of which the N-terminal propeptide …

[HTML][HTML] 一株海洋来源铜绿假单胞菌Gxun-7 角蛋白酶基因的克隆, 表达及重组酶酶学性质

杨梦莹, 谢晨杰, 李时勇, 张红岩, 王一兵… - 微生物学 …, 2022 - wswxtb.ijournals.cn
[背景] 角蛋白酶是一类特异性降解角蛋白的水解酶, 在动物饲料, 生物肥料, 医学, 洗涤,
制革及环境治理等方面具有重要的应用潜力.[目的] 对前期从海洋环境筛选出的一株铜绿假单胞 …

Understanding enzyme-mediated keratin hydrolysis and evaluation of new keratin binding peptides

J Pinheiro De Oliveira Martinez - 2023 - eprints.qut.edu.au
Keratin is the main structural protein in hair, wool, nails, horns, and hooves. This study
explored the potential of waste keratin as a resource for new products. Enzymatic hydrolysis …