Application of mesenchymal stem cells for therapeutic agent delivery in anti-tumor treatment

DS Chulpanova, KV Kitaeva, LG Tazetdinova… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stem cells (MSCs) are non-hematopoietic progenitor cells, which can be
isolated from different types of tissues including bone marrow, adipose tissue, tooth pulp …

Mesenchymal stem cells, exosomes and exosome-mimics as smart drug carriers for targeted cancer therapy

H Liu, S Deng, L Han, Y Ren, J Gu, L He, T Liu… - Colloids and Surfaces B …, 2022 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity to differentiate
into several cell types under appropriate conditions. They also possess remarkable …

The dual role of mesenchymal stem cells in cancer pathophysiology: pro-tumorigenic effects versus therapeutic potential

Y Slama, F Ah-Pine, M Khettab, A Arcambal… - International Journal of …, 2023 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells involved in numerous
physiological events, including organogenesis, the maintenance of tissue homeostasis …

[PDF][PDF] RETRACTED: Mesenchymal Stem/Stromal Cells as a Vehicle for Cytokine Delivery: An Emerging Approach for Tumor Immunotherapy

E Razeghian, R Margiana, S Chupradit… - Frontiers in …, 2021 - frontiersin.org
Pro-inflammatory cytokines can effectively be used for tumor immunotherapy, affecting every
step of the tumor immunity cycle. Thereby, they can restore antigen priming, improve the …

TRAIL-based gene delivery and therapeutic strategies

H Zhong, H Wang, J Li, Y Huang - Acta Pharmacologica Sinica, 2019 - nature.com
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), also known as APO2L,
belongs to the tumor necrosis factor family. By binding to the death receptor 4 (DR4) or DR5 …

Scalable manufacturing of gene-modified human mesenchymal stromal cells with microcarriers in spinner flasks

PS Couto, DJ Stibbs, MC Rotondi, Y Takeuchi… - Applied Microbiology …, 2023 - Springer
Due to their immunomodulatory properties and in vitro differentiation ability, human
mesenchymal stromal cells (hMSCs) have been investigated in more than 1000 clinical trials …

Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy

F Rossignoli, G Grisendi, C Spano, G Golinelli… - Cancer Gene …, 2019 - nature.com
Cellular therapies based on mesenchymal stromal/stem cells (MSC) are promising
strategies in regenerative medicine and oncology. Despite encouraging results, there is still …

[PDF][PDF] RETRACTED: Mesenchymal Stem/Stromal Cell-Based Delivery: A Rapidly Evolving Strategy for Cancer Therapy

A Hassanzadeh, AH Altajer, HS Rahman… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stem/stromal cell (MSC)-based therapy has become an attractive and
advanced scientific research area in the context of cancer therapy. This interest is closely …

[HTML][HTML] The role of TRAIL signaling in cancer: searching for new therapeutic strategies

C Luo, S He, F Shi, J Zhou, L Shang - Biology, 2024 - mdpi.com
Simple Summary In the realm of modern medicine, the battle against cancer is a relentless
pursuit that demands continuous innovation. Among the numerous elements in the complex …

Chorioallantoic membrane assay at the cross-roads of adipose-tissue-derived stem cell research

D Oliinyk, A Eigenberger, O Felthaus, S Haerteis… - Cells, 2023 - mdpi.com
With a history of more than 100 years of different applications in various scientific fields, the
chicken chorioallantoic membrane (CAM) assay has proven itself to be an exceptional …