Liver cancer is the second leading cause of cancer‐related deaths, and hepatocellular
carcinoma (HCC) is the most common type. Therefore, molecular targets are urgently …

Hepatocellular carcinoma (HCC) is among the most lethal and prevalent cancers in the
human population. Different etiological factors such as hepatitis B and C virus, alcohol and …

Background Alcohol related liver disease (ARLD) is one of the major chronic liver diseases
worldwide. This review aimed to describe the global prevalence, incidence, and outcomes of …

The tumor microenvironment (TME) is influenced by a" disorganized" extracellular matrix
(ECM) that sensitizes cancer cells toward mechanical stress, signaling, and structural …

Acute respiratory distress syndrome (ARDS) and hospital-acquired pneumonia (HAP) are
major problems of public health in intensive care units (ICUs), occurring in 15% of critically ill …

Syndecan-1 (SDC1, CD138) is one of the heparan sulfate proteoglycans and is essential for
maintaining normal cell morphology, interacting with the extracellular and intracellular …

Cell surface proteoglycans are known to be important regulators of many aspects of cell
behavior. The principal family of transmembrane proteoglycans is the syndecans, of which …

Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain,
such as a heparan, dermatan, chondroitin, or keratan sulfate, covalently attached to the …

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and one of the
leading causes of cancer-related death worldwide. HCC is highly heterogeneous, both …

Introduction The endothelial surface layer is covered with abundant proteoglycans, of which
syndecans and glycosaminoglycans are major constituents. Recent Findings Among the …