Synthesis of new 1, 2, 4-triazole compounds containing Schiff and Mannich bases (morpholine) with antioxidant and antimicrobial activities

Y Ünver, S Deniz, F Çelik, Z Akar, M Küçük… - Journal of Enzyme …, 2016 - Taylor & Francis
Compound 2 was synthesized by reacting CS2/KOH with compound 1. The treatment of
compound 2 with hydrazine hydrate produced compound 3. Then, compound 3 was …

New thiophene-1, 2, 4-triazole-5 (3)-ones: Highly bioactive thiosemicarbazides, structures of Schiff bases and triazole–thiols

Y Ünver, K Sancak, F Çelik, E Birinci, M Küçük… - European journal of …, 2014 - Elsevier
Abstract Key compound 2-(4-amino-5-oxo-3-(thiophene-2-ylmethyl)-4, 5-dihydro-1, 2, 4-
tiazole-1-yl) acetohydrazide (3) was synthesized by reacting hydrazine hydrate with ethyl-2 …

Synthesis and Screening of New [1,3,4]Oxadiazole, [1,2,4]Triazole, and [1,2,4]Triazolo[4,3-b][1,2,4]triazole Derivatives as Potential Antitumor Agents on the Colon …

EM Abdelrehim - ACS omega, 2021 - ACS Publications
New derivatives of [1, 3, 4] oxadiazole-2-thione and triazole-3-thione were synthesized
through the cyclocondensation of dicarbonyl ester 2 with phenyl hydrazine followed by …

1, 2, 4-triazole-3-thione Schiff bases compounds: Crystal structure, hirshfeld surface analysis, DFT studies and biological evaluation

S Wu, L Qi, Y Ren, H Ma - Journal of Molecular Structure, 2020 - Elsevier
Three novel Schiff base compounds (G 1, G 2 and G 3) were synthesized and characterized
by elemental analysis, FT-IR, NMR, and X-ray single crystal diffraction. The crystal structures …

[HTML][HTML] New synthetic 1, 2, 4-triazole derivatives: Cholinesterase inhibition and molecular docking studies

N Riaz, M Iftikhar, M Saleem, S Hussain, F Rehmat… - Results in …, 2020 - Elsevier
Two series of new N-aryl derivatives (9a-j; 10a-j) of 2-(4-ethyl-5-(3-chlorophenyl)-4H-1, 2, 4-
triazol-3-ylthio) acetamide and 2-(4-phenyl-5-(3-chlorophenyl)-4H-1, 2, 4-triazol-3-ylthio) …

1, 2, 4-Triazole derivative containing thiophen ring: Comparison of theoretical IR and NMR data with experimental

F Çelik, Y Ünver - Journal of the Indian Chemical Society, 2022 - Elsevier
Abstract The molecular structure of 1, 2, 4-triazole containing thiophene derivative which
called as ethyl-2-(4-amino-5-oxo-3-(thiophene-2-ylmethyl)-4, 5-dihydro-1, 2, 4-triazole-1-yl) …

Synthesis, crystal structure, and antioxidant properties of novel 1, 2, 4-triazol-5-ones containing 3, 4-dimethoxyphenyl and 3, 4-dihydroxyphenyl moiety

Y ÜNVER, S Meydanal, K Sancak… - Turkish Journal of …, 2011 - journals.tubitak.gov.tr
Abstract A series of new 4-(3, 4-dimethoxyphenethyl)-5-akyl/aryl-2H-1, 2, 4-triazol-3 (4H)-
ones (3a-g) was obtained by the reaction of ethyl 2-(ethoxy)(alkylidene/arylidene) …

Stereoselective Asymmetric Syntheses of Molecules with a 4,5-Dihydro-1H-[1,2,4]-Triazoline Core Possessing an Acetylated Carbohydrate Appendage: Crystal …

AS Al Maqbali, NK Al Rasbi, WM Zoghaib, N Sivakumar… - Molecules, 2024 - mdpi.com
A new series of chiral 4, 5-dihydro-1 H-[1, 2, 4]-triazoline molecules, featuring a β-ᴅ-
glucopyranoside appendage, were synthesized via a 1, 3-dipolar cycloaddition reaction …

Green synthesis and acetylcholinesterase inhibition of coumarin-1, 2, 4-triazole hybrids

M Karnaš, V Rastija, D Šubarić… - Current organic …, 2023 - benthamdirect.com
The pursuit of biologically active compounds has led many researchers to synthesize
different heterocyclic hybrids with prominent activity. Both coumarin and 1, 2, 4-triazole are …

Bis-1, 2, 4-triazol derivatives: Synthesis, characterization, DFT, antileishmanial activity and molecular docking study

N Süleymanoğlu, R Ustabaş, Hİ Güler… - Journal of …, 2023 - Taylor & Francis
In this study, triazol derivatives, 4, 4'-(((1E, 1E')-1, 2-phenylenebis (methanylyidene)) bis
(azanylidene)) bis (5-methyl-2, 4-dihydro-3 H-1, 2, 4-triazol-3-one (2), 4, 4'-(((1E, 1E')-1, 3 …