Oligodendrocytes are best known for wrapping myelin, a unique specialization that enables energy-efficient and fast axonal impulse propagation in white matter tracts and fibers of the …
Brain function requires a constant supply of glucose. However, the brain has no known energy stores, except for glycogen granules in astrocytes. In the present study, we report that …
KA Nave, HB Werner - Annual Review of Neuroscience, 2021 - annualreviews.org
Myelination of axons provides the structural basis for rapid saltatory impulse propagation along vertebrate fiber tracts, a well-established neurophysiological concept. However …
F Bouçanova, R Chrast - Frontiers in cellular neuroscience, 2020 - frontiersin.org
Recent research into axon-glial interactions in the nervous system has made a compelling case that glial cells have a relevant role in the metabolic support of axons, and that, in the …
MT Weil, S Heibeck, M Töpperwien… - Journal of …, 2018 - Soc Neuroscience
In the nervous system, myelination of axons enables rapid impulse conduction and is a specialized function of glial cells. Myelinating glia are the last cell type to emerge in the …
Neuronal functions and impulse propagation depend on the continuous supply of glucose,. Surprisingly, the mammalian brain has no obvious energy stores, except for astroglial …
We reveal that lipid turnover in the myelin sheath generates a fatty acid pool in oligodendrocytes that can contribute to the energy balance of white matter tracts. We also …
L Sheng, J Gao, Q Wei, Y Gong, ZX Xu - Cell Reports, 2025 - cell.com
Lipid droplets (LDs) are dynamic organelles essential for lipid storage and organismal survival. Studies have highlighted the importance of glial function in brain LD formation …
B Zhang, J Chen, J Wang, X Pan - Environmental Pollution, 2025 - Elsevier
The long-term harmful effects of arsenic exposure remain one of the important public health issues. The effects of arsenic exposure on the central nervous system, particularly …