A comprehensive approach to Parkinson's disease: addressing its molecular, clinical, and therapeutic aspects

M Muleiro Alvarez, G Cano-Herrera… - International journal of …, 2024 - mdpi.com
Parkinson's disease (PD) is a gradually worsening neurodegenerative disorder affecting the
nervous system, marked by a slow progression and varied symptoms. It is the second most …

[HTML][HTML] Parkin type of early-onset Parkinson disease

N Brüggemann, C Klein - 2020 - europepmc.org
Parkin type of early-onset Parkinson disease (PARK-Parkin) is characterized by the cardinal
signs of Parkinson disease (PD): bradykinesia, resting tremor, and rigidity. The median age …

Parkin is the most common causative gene in a cohort of mainland Chinese patients with sporadic early‐onset Parkinson's disease

Y Jiang, M Yu, J Chen, H Zhou, W Sun… - Brain and …, 2020 - Wiley Online Library
Introduction Genetic mutations associated with early‐onset Parkinson's disease (EOPD)
vary widely among different ethnicities. We detected the genes associated with EOPD in a …

Effects of a Concurrent Working Memory Task on Speech Acoustics in Parkinson's Disease

DA Dragicevic, KL Dahl, Z Perkins, D Abur… - American journal of …, 2024 - ASHA
Purpose: The purpose of this study was to determine the effect of a concurrent working
memory task on acoustic measures of speech in individuals with Parkinson's disease (PD) …

Quality of Life in Newly Diagnosed Patients With Parkin-Related Parkinson's Disease

XY Zhou, FT Liu, C Chen, SS Luo, J Zhao… - Frontiers in …, 2020 - frontiersin.org
Introduction: Mutations in the Parkin gene are the most common cause of autosomal
recessive early-onset Parkinson's disease (PD). However, little is known about the quality of …

[HTML][HTML] Total physical activity, plant-based diet and neurodegenerative diseases: A prospective cohort study of the UK biobank

X Zheng, J Liu, S Wang, Y Xiao, Q Jiang, C Li… - Parkinsonism & Related …, 2024 - Elsevier
Abstract Introduction Neurodegenerative diseases (NDDs) result from a complex interplay of
genetic, environmental and aging factors. A balanced diet and adequate physical activity …

Clinical phenotype of Parkinson's disease with a homozygous PRKN p. Cys441Arg mutation.

SY Lim, A Ahmad-Annuar, K Lohmann… - Neurology …, 2021 - search.ebscohost.com
We describe the clinical features of a Malaysian woman with Parkinson's disease (PD) who
carried the PRKN p. Cys441Arg mutation in the homozygous state. She had a fairly" classic" …

Pitfalls and caveats in the diagnostic pathway of people with Parkinson's disease

A Cervantes-Arriaga, C Sarabia-Tapia… - Revista mexicana de …, 2022 - scielo.org.mx
CERVANTES-ARRIAGA, Amin et al. Pitfalls and caveats in the diagnostic pathway of people
with Parkinson's disease. Rev. mex. neurocienc.[online]. 2022, vol. 23, n. 4, pp. 119-125 …

[PDF][PDF] Jaunatvinio parkinsonizmo diagnostikos problemos. Klinikinis atvejis

D Bučaitė, O Laucius, E Pajėdienė - … Vilnius: Sveikatos mokslai, 2023, t. 33 …, 2023 - sm-hs.eu
Parkinsono liga (PL) dažniausiai serga vyresni nei 60 metų asmenys. Jei klinikiniai šio
sutrikimo simptomai pasireiškia iki 21 metų, diagnozuojamas jaunatvinis parkinsonizmas …