Abstract The 1, 2, 3-triazole ring is a major pharmacophore system among nitrogen-
containing heterocycles. These five-membered heterocyclic motifs with three nitrogen …

Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …

Fluoroquinolones remain one of the most important kind of antibacterial agents used
nowadays. The emergence of more virulent and resistant strains of bacteria by the …

Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …

A new type of benzopyrone-mediated quinolones (BMQs) was rationally designed and
efficiently synthesized as novel potential antibacterial molecules to overcome the global …

Bacterial infection is amongst the most common diseases in community and hospital
settings. Fluoroquinolones, exerting the antibacterial activity through binding to type II …

At present therapeutic options for severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) are very limited. We designed and synthesized three sets of small molecules using …

This review is aimed to provide extensive survey of quinolones and fluoroquinolones for a
variety of applications ranging from metal complexes and nanoparticle development to …

Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

Background Nitrogen heterocyclic rings and sulfonamides have attracted attention of several
researchers. Results A series of regioselective imidazole-based mono-and bis-1, 4 …