Neuroinflammation is a common pathological feature of amyotrophic lateral sclerosis (ALS).
Although scientific evidence to date does not allow defining neuroinflammation as an ALS …

Glioblastoma (GB) tumors are one of the most insidious cancers which take over the brain
and defy therapy. Over time and in response to treatment the tumor and the brain cells in the …

In recent years, lipid metabolism has gained greater attention in several diseases including
cancer. Dysregulation of fatty acid metabolism is a key component in breast cancer …

Extracellular vesicle (EV) secretion is a ubiquitous cellular process with both physiologic
and pathologic consequences. EVs are small lipid bilayer vesicles that encompass both …

Cancer cells actively release lipid bilayer extracellular vesicles (EVs) that affect their
microenvironment, favoring their progression and response to extracellular stress. These …

Simple Summary This study aims to explore metabolic remodeling in plasma and tissue
samples in patients with glioblastoma through an integrated targeted and untargeted …

The microenvironment (ME) plays a critical role in causing glioblastoma (GBM) to be a
moving and incurable target. The main features governing the interaction between cancer …

Extracellular vesicles (EVs) are membranous nanoparticles secreted by almost all cell types.
Reflecting the physiopathological state of the parental cell, EVs circulate in all body fluids …

Glioblastoma (GB) is an aggressive type of tumour for which therapeutic options and
biomarkers are limited. GB diagnosis mostly relies on symptomatic presentation of the …

Background Macrophages release not only cytokines but also extracellular vesicles (EVs).
which are small membrane-derived nanovesicles with virus-like properties transferring …