Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials
Background and aims Vitamin C has been used as an anti-oxidant in various diseases
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …
including viral illnesses like coronavirus disease (COVID-19). Methods Meta-analysis of …
Targeting oxidative stress in septic acute kidney injury: from theory to practice
Sepsis is the leading cause of acute kidney injury (AKI) and leads to increased morbidity
and mortality in intensive care units. Current treatments for septic AKI are largely supportive …
and mortality in intensive care units. Current treatments for septic AKI are largely supportive …
ESPEN practical short micronutrient guideline
Background Trace elements and vitamins, named together micronutrients (MNs), are
essential for human metabolism. The importance of MNs in common pathologies is …
essential for human metabolism. The importance of MNs in common pathologies is …
Therapeutic potential of megadose vitamin C to reverse organ dysfunction in sepsis and COVID‐19
Sepsis induced by bacteria or viruses can result in multiorgan dysfunction, which is a major
cause of death in intensive care units. Current treatments are only supportive, and there are …
cause of death in intensive care units. Current treatments are only supportive, and there are …
Emerging benefits and drawbacks of α2‐adrenoceptor agonists in the management of sepsis and critical illness
Agonists of α2‐adrenoceptors are increasingly being used for the provision of comfort,
sedation and the management of delirium in critically ill patients, with and without sepsis. In …
sedation and the management of delirium in critically ill patients, with and without sepsis. In …
An update on essential micronutrients in critical illness
KWA Koekkoek, MM Berger - Current Opinion in Critical Care, 2023 - journals.lww.com
The needs in critical illness are higher than those of healthy individuals and must be
covered to support immunity. Monitoring selected micronutrients is justified in patients …
covered to support immunity. Monitoring selected micronutrients is justified in patients …
Mega-dose sodium ascorbate: a pilot, single-dose, physiological effect, double-blind, randomized, controlled trial
Background Mega-dose sodium ascorbate (NaAscorbate) appears beneficial in
experimental sepsis. However, its physiological effects in patients with septic shock are …
experimental sepsis. However, its physiological effects in patients with septic shock are …
Vitamin C alleviates LPS-induced myocardial injury by inhibiting pyroptosis via the ROS-AKT/mTOR signalling pathway
P Zhang, M Zang, Z Sang, Y Wei, Y Yan, X Bian… - BMC cardiovascular …, 2022 - Springer
Background The efficacy of vitamin C in sepsis remains controversial. Whether vitamin C
can alleviate lipopolysaccharide (LPS)-induced myocardial injury by inhibiting pyroptosis …
can alleviate lipopolysaccharide (LPS)-induced myocardial injury by inhibiting pyroptosis …
Vitamin C for sepsis intervention: from redox biochemistry to clinical medicine
YR Li, H Zhu - Molecular and cellular biochemistry, 2021 - Springer
Vitamin C, also known as ascorbic acid or ascorbate, is a water-soluble vitamin synthesized
in plants as well as in animals except humans and several other animal species. Humans …
in plants as well as in animals except humans and several other animal species. Humans …
Neuroprotective properties of vitamin C: a scoping review of pre-clinical and clinical studies
There is a need for novel neuroprotective therapies. We aimed to review the evidence for
exogenous vitamin C as a neuroprotective agent. MEDLINE, Embase, and Cochrane library …
exogenous vitamin C as a neuroprotective agent. MEDLINE, Embase, and Cochrane library …