The neurobiology of tumors has attracted considerable interest from clinicians and scientists
and has become a multidisciplinary area of research. Neural components not only interact …

Abstract Doublecortin-like kinase 1 (DCLK1), a significant constituent of the protein kinase
superfamily and the doublecortin family, has been recognized as a prooncogenic factor that …

Simple Summary In this study, we found that the novel small molecule kinase inhibitor
DCLK1-IN-1 not only inhibited DCLK1 phosphorylation, stemness, and EMT-related …

Abstract Doublecortin‐like kinase 1 (DCLK1) is a putative cancer stem cell marker, a
promising diagnostic and prognostic maker for malignant tumors and a proposed driver …

Despite recent advancements, the 5 year survival of head and neck squamous cell
carcinoma (HNSCC) hovers at 60%. DCLK1 has been shown to regulate epithelial-to …

Background Oral squamous cell carcinoma (OSCC) is a frequently-diagnosed malignancy
with high potential for proliferation and invasion. Histone methylation is known as a crucial …

Doublecortin-like kinase 1 (DCLK1) is a functional serine/threonine (S/T)-kinase and a
member of the doublecortin family of proteins which are characterized by their ability to bind …

Objectives About 17% of patients with human papillomavirus (HPV)‐positive head and neck
squamous cell carcinoma (HNSCC), which is mainly comprised of oropharyngeal SCC …

The field of stem cell research has opened exciting new avenues for developing stem cell-
based therapies for the regeneration of tissues (see Chapter 16) or the treatment of cancers …

ABSTRACT Doublecortin like kinase 1 (DCLK1) is a microtubule associated protein and
Ser/Thr-protein kinase family member, hence important for cellular shape, polarity …