Current status and future trends of the global burden of MASLD

L Miao, G Targher, CD Byrne, YY Cao… - Trends in Endocrinology & …, 2024 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as the most
common chronic liver disease globally, affecting more than a third of the world's adult …

The role of complement in nonalcoholic fatty liver disease

Z Guo, X Fan, J Yao, S Tomlinson, G Yuan… - Frontiers in …, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of chronic liver
diseases globally. NAFLD includes a range of hepatic manifestations, starting with liver …

Farnesoid X receptor, bile acid metabolism, and gut microbiota

H Mori, G Svegliati Baroni, M Marzioni, F Di Nicola… - Metabolites, 2022 - mdpi.com
Obesity, type 2 diabetes, and non-alcoholic fatty liver disease (NAFLD) are characterized by
the concepts of lipo-and glucotoxicity. NAFLD is characterized by the accumulation of …

Advances in genetic variation in metabolism-related fatty liver disease

F Shi, M Zhao, S Zheng, L Zheng, H Wang - Frontiers in Genetics, 2023 - frontiersin.org
Metabolism-related fatty liver disease (MAFLD) is the most common form of chronic liver
disease in the world. Its pathogenesis is influenced by both environmental and genetic …

Discovery of the first-in-class intestinal restricted FXR and FABP1 dual modulator ZLY28 for the treatment of nonalcoholic fatty liver disease

Q Ren, Y Chen, Z Zhou, Z Cai, S Jiao… - Journal of Medicinal …, 2023 - ACS Publications
The prevalence of nonalcoholic steatohepatitis (NASH) is increasing rapidly worldwide, and
NASH has become a serious problem for human health. Recently, the selective activation of …

Association of complement components with the risk and severity of NAFLD: A systematic review and meta-analysis

J Zhao, Y Wu, P Lu, X Wu, J Han, Y Shi, Y Liu… - Frontiers in …, 2022 - frontiersin.org
Background It is generally believed that complement system is strongly associated with the
risk of nonalcoholic fatty liver disease (NAFLD). However, complement system contains a …

The presence and severity of NAFLD are associated with cognitive impairment and hippocampal damage

Y Miao, B Zhang, X Sun, X Ma, D Fang… - The Journal of …, 2023 - academic.oup.com
Context Although cognitive impairment in nonalcoholic fatty liver disease (NAFLD) has
received attention in recent years, little is known about detailed cognitive functions in …

Berberine ameliorates metabolic-associated fatty liver disease mediated metabolism disorder and redox homeostasis by upregulating clock genes: Clock and Bmal1 …

C Ye, Y Zhang, S Lin, Y Chen, Z Wang, H Feng, G Fang… - Molecules, 2023 - mdpi.com
Metabolic-associated fatty liver disease (MAFLD) is one of the most common chronic liver
diseases, which in turn triggers mild inflammation, metabolic dysfunction, fibrosis, and even …

Low-carbohydrate and low-fat diet with metabolic-dysfunction-associated fatty liver disease

C Hu, R Huang, R Li, N Ning, Y He, J Zhang, Y Wang… - Nutrients, 2023 - mdpi.com
Background: This observational cross-sectional study was designed to explore the effects of
a low-carbohydrate diet (LCD) and a low-fat diet (LFD) on metabolic-dysfunction-associated …

Emerging trends and hotspots in the links between the gut microbiota and MAFLD from 2002 to 2021: a bibliometric analysis

Y Li, Y Zhou, L Wang, X Lin, M Mao, S Yin… - Frontiers in …, 2022 - frontiersin.org
Background The prevalence of metabolic associated fatty liver disease (MAFLD) presented
a booming growth over recent years in the whole world. MAFLD was associated with a …