Site-predictable and chemoselective C–H bond functionalization reactions offer synthetically
powerful strategies for the step-economic diversification of both feedstock and fine …

Transition-metal-catalyzed, coordination-assisted C (sp3)–H functionalization has
revolutionized synthetic planning over the past few decades as the use of these directing …

During the past decades, synthetic organic chemistry discovered that directing group
assisted C–H activation is a key tool for the expedient and siteselective construction of C–C …

The late‐stage modification of structurally complex peptides bears great potential for drug
discovery, crop protection, and the pharmaceutical industry, among others. Whereas …

The amidated peptides are an important class of biologically active compounds due to their
unique biological properties and wide applications as potential peptide drugs and …

Bioorthogonal late‐stage diversification of structurally complex peptides bears enormous
potential for drug discovery and molecular imaging, among other applications. Herein, we …

Disclosed herein is the visible‐light‐promoted deaminative C (sp3)− H alkylation of glycine
and peptides using Katritzky salts as electrophiles. Simple reaction conditions and excellent …

The site‐selective functionalization of unactivated C (sp3)− H bonds remains one of the
greatest challenges in organic synthesis. Herein, we report on the site‐selective δ‐C (sp3) …

Cyclic peptides have attracted tremendous attention in the pharmaceutical industry owing to
their excellent cell penetrability, stability, thermostability, and drug-like properties. However …

The late-stage functionalization (LSF) of pharmaceutical and agrochemical compounds by
the site-selective activation of C–H bonds provides access to diverse structural analogs and …