Active targeted nanoformulations via folate receptors: State of the art and future perspectives

C Martín-Sabroso, AI Torres-Suárez… - Pharmaceutics, 2021 - mdpi.com
In normal tissues, the expression of folate receptors is low and limited to cells that are
important for embryonic development or for folate reabsorption. However, in several …

Strategic Developments in Polymer-Functionalized Liposomes for Targeted Colon Cancer Therapy: An Updated Review of Clinical Trial Data and Future Horizons

S Sharma, M Chakraborty, D Yadav, A Dhullap… - …, 2024 - ACS Publications
Liposomes, made up of phospholipid bilayers, are efficient nanocarriers for drug delivery
because they can encapsulate both hydrophilic and lipophilic drugs. Conventional cancer …

Actively targeted nanomedicines in breast cancer: from pre-clinal investigation to clinic

AI Fraguas-Sánchez, I Lozza, AI Torres-Suárez - Cancers, 2022 - mdpi.com
Simple Summary Despite all the efforts and advances made in the treatment of breast
cancer, this pathology continues to be one of the main causes of cancer death in women …

Antibody-antineoplastic conjugates in gynecological malignancies: current status and future perspectives

C Martin-Sabroso, I Lozza, AI Torres-Suarez… - Pharmaceutics, 2021 - mdpi.com
In the last decade, antibody-drug conjugates (ADCs), normally formed by a humanized
antibody and a small drug via a chemical cleavable or non-cleavable linker, have emerged …

An olive oil mill wastewater extract improves chemotherapeutic activity against breast cancer cells while protecting from cardiotoxicity

N Benedetto, L Calabrone, K Gutmańska… - Frontiers in …, 2022 - frontiersin.org
Cardiovascular toxicity in cancer patients receiving chemotherapy remains one of the most
undesirable side effects, limiting the choice of the most efficient therapeutic regimen …

Research progress on gene editing based on nano-drug delivery vectors for tumor therapy

S Xi, YG Yang, J Suo, T Sun - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Malignant tumors pose a serious threat to human health and have high fatality rates.
Conventional clinical anti-tumor treatment is mainly based on traditional surgery …

Current Perspectives on Nanoparticle-based Targeted Drug Delivery Approaches in Breast Cancer Treatment

P Pandey, F Khan, R Maqsood… - Endocrine, Metabolic & …, 2023 - ingentaconnect.com
Breast cancer is avertible yet one of the most widespread carcinomas globally. Though
periodic screening and monitoring have resulted in reduced incidences, the malignancy …

Biomarking and induction of apoptosis in ovarian cancer using bifunctional polyethyleneimine-caged platinum nanoclusters

M Zhang, H Yue, Y Liu, H Li, Y Yin, Z Sun, P Cui… - Frontiers in …, 2022 - frontiersin.org
According to the 2020 GLOBOCAN Global Cancer Women's Cancer Data, ovarian cancer is
the eighth most common tumor in humans. Still, its mortality rate ranks first among all …

Nanomedicine Applications in Cancer Treatment

AI Fraguas-Sánchez, C Martín-Sabroso, I Lozza… - Handbook of Cancer …, 2023 - Springer
Despite all the advances made, cancer continues to be one of the main pathologies,
responsible for almost ten million deaths worldwide in 2020, being lung cancer, colon …

Nanomedicine as a Novel Strategy to Target Tumor Immune Microenvironment: Current State and Future Perspectives

AI Fraguas-Sánchez, C Martín-Sabroso… - Handbook of Cancer …, 2022 - Springer
Nanomedicine that consists of using nanotechnology-based therapeutics has proven to be
very useful in oncology, being widely exploited for the administration of chemotherapeutics …