Head and neck squamous cell carcinoma (HNSCC), one of the most common types of
cancers occurring in the head and neck region, is often associated with high mortality rates …

Microbes in marine ecosystems have evolved their gene content to thrive successfully in the
cold. Although this process has been reasonably well studied in bacteria and selected …

Determining precise locations of hydrogen atoms in enzyme active sites, especially those in
the reaction intermediates, provides important information for understanding the structure …

Extracellular signal-regulated kinase 2 (ERK2), a mitogen-activated protein kinase (MAPK),
plays an essential role in physiological cellular processes and is a drug target for treating …

The stabilization of the retromer protein complex can be effective in the treatment of different
neurological disorders. Following the identification of bis-1, 3-phenyl guanylhydrazone 2a …

The pressing challenge of cancer's high mortality and invasiveness demands improved
therapeutic approaches. Targeting the nutrient dependencies within cancer cells has …

Molecular Dynamics is widely utilized in the fields of chemistry, physics, and material
science, offering deep insights into complex systems. However, it is constrained by the …