Personalized management of pheochromocytoma and paraganglioma

S Nölting, N Bechmann, D Taieb… - Endocrine …, 2022 - academic.oup.com
Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape
that allows their assignment to clusters based on underlying genetic alterations. With around …

An overview of 20 years of genetic studies in pheochromocytoma and paraganglioma

A Buffet, N Burnichon, J Favier… - Best practice & research …, 2020 - Elsevier
Paragangliomas and pheochromocytomas (PPGL) are rare neuroendocrine tumours
characterized by a strong genetic determinism. Over the past 20 years, evolution of PPGL …

Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas

R García-Carbonero, F Matute Teresa… - Clinical and …, 2021 - Springer
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that
arise from chromaffin cells of the adrenal medulla and the sympathetic/parasympathetic …

The North American Neuroendocrine Tumor Society consensus guidelines for surveillance and management of metastatic and/or unresectable pheochromocytoma …

L Fishbein, J Del Rivero, T Else, JR Howe, SL Asa… - Pancreas, 2021 - journals.lww.com
This manuscript is the result of the North American Neuroendocrine Tumor Society
consensus conference on the medical management and surveillance of metastatic and …

Metastatic pheochromocytomas and abdominal paragangliomas

D Granberg, CC Juhlin… - The journal of clinical …, 2021 - academic.oup.com
Abstract Context Pheochromocytomas and paragangliomas (PPGLs) are believed to harbor
malignant potential; about 10% to 15% of pheochromocytomas and up to 50% of abdominal …

New insights on the genetics of pheochromocytoma and paraganglioma and its clinical implications

S Jhawar, Y Arakawa, S Kumar, D Varghese, YS Kim… - Cancers, 2022 - mdpi.com
Simple Summary Pheochromocytoma and paraganglioma (together PPGL) are rare
neuroendocrine tumors that arise from chromaffin tissue and produce catecholamines …

Genetic bases of pheochromocytoma and paraganglioma

A Cascón, B Calsina, M Monteagudo… - Journal of …, 2023 - jme.bioscientifica.com
The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly
complex over the last two decades. The list of genes involved in the development of these …

Pheochromocytoma: a changing perspective and current concepts

A Kiriakopoulos, P Giannakis… - … in endocrinology and …, 2023 - journals.sagepub.com
This article aims to review current concepts in diagnosing and managing
pheochromocytoma and paraganglioma (PPGL). Personalized genetic testing is vital, as 40 …

Metabolic enzyme DLST promotes tumor aggression and reveals a vulnerability to OXPHOS inhibition in high-risk neuroblastoma

NM Anderson, X Qin, JM Finan, A Lam, J Athoe… - Cancer research, 2021 - AACR
High-risk neuroblastoma remains therapeutically challenging to treat, and the mechanisms
promoting disease aggression are poorly understood. Here, we show that elevated …

Ovarian cancer modulates the immunosuppressive function of CD11b+ Gr1+ myeloid cells via glutamine metabolism

MP Udumula, S Sakr, S Dar, AB Alvero, R Ali-Fehmi… - Molecular …, 2021 - Elsevier
Abstract Objective Immature CD11b+ Gr1+ myeloid cells that acquire immunosuppressive
capability, also known as myeloid-derived suppressor cells (MDSCs), are a heterogeneous …