The autonomic nervous system and heart failure

VG Florea, JN Cohn - Circulation research, 2014 - Am Heart Assoc
The pathophysiology of heart failure (HF) is characterized by hemodynamic abnormalities
that result in neurohormonal activation and autonomic imbalance with increase in …

Cardiac innervation and sudden cardiac death

K Fukuda, H Kanazawa, Y Aizawa, JL Ardell… - Circulation …, 2015 - Am Heart Assoc
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …

Sympathetic nervous system overactivity and its role in the development of cardiovascular disease

SC Malpas - Physiological reviews, 2010 - journals.physiology.org
This review examines how the sympathetic nervous system plays a major role in the
regulation of cardiovascular function over multiple time scales. This is achieved through …

Heart–brain axis: effects of neurologic injury on cardiovascular function

P Tahsili-Fahadan, RG Geocadin - Circulation research, 2017 - Am Heart Assoc
A complex interaction exists between the nervous and cardiovascular systems. A large
network of cortical and subcortical brain regions control cardiovascular function via the …

Sympathetic nervous system activation in human heart failure: clinical implications of an updated model

JS Floras - Journal of the American College of cardiology, 2009 - jacc.org
Disturbances in cardiovascular neural regulation, influencing both disease course and
survival, progress as heart failure worsens. Heart failure due to left ventricular systolic …

The sympathetic/parasympathetic imbalance in heart failure with reduced ejection fraction

JS Floras, P Ponikowski - European heart journal, 2015 - academic.oup.com
Cardiovascular autonomic imbalance, a cardinal phenotype of human heart failure, has
adverse implications for symptoms during wakefulness and sleep; for cardiac, renal, and …

First-in-man safety evaluation of renal denervation for chronic systolic heart failure: primary outcome from REACH-Pilot study

JE Davies, CH Manisty, R Petraco, AJ Barron… - International journal of …, 2013 - Elsevier
BACKGROUND: Sympathetic overactivation, is reduced by renal denervation in drug-
resistant hypertension. A similar role for renal denervation in heart failure remains …

Metabolic mechanisms in heart failure

H Ashrafian, MP Frenneaux, LH Opie - Circulation, 2007 - Am Heart Assoc
Although neurohumoral antagonism has successfully reduced heart failure morbidity and
mortality, the residual disability and death rate remains unacceptably high. Though …

[图书][B] Guyton y Hall. Tratado de fisiología médica

JE Hall - 2011 - books.google.com
Nueva edición del best seller en fisiología, y el libro más valorado por los estudiantes de
Medicina a la hora de afrontar la asignatura de la Fisiología, uno de los pilares …

Angiotensin‐converting enzyme 2 in the brain: properties and future directions

H Xia, E Lazartigues - Journal of neurochemistry, 2008 - Wiley Online Library
Abstract Angiotensin (Ang)‐converting enzyme (ACE) 2 cleaves Ang‐II into the vasodilator
peptide Ang‐(1–7), thus acting as a pivotal element in balancing the local effects of these …