FLT3 inhibitors in acute myeloid leukemia

M Wu, C Li, X Zhu - Journal of hematology & oncology, 2018 - Springer
FLT3 mutations are one of the most common findings in acute myeloid leukemia (AML).
FLT3 inhibitors have been in active clinical development. Midostaurin as the first-in-class …

Therapeutic approaches for Non-melanoma skin Cancer: Standard of Care and Emerging modalities

S Sol, F Boncimino, K Todorova, SE Waszyn… - International Journal of …, 2024 - mdpi.com
Skin cancer encompasses a range of cutaneous malignancies, with non-melanoma skin
cancers (NMSCs) being the most common neoplasm worldwide. Skin exposure is the …

Merkel cell carcinoma: An updated review of pathogenesis, diagnosis, and treatment options

LE Hernandez, N Mohsin, M Yaghi… - Dermatologic …, 2022 - Wiley Online Library
Merkel cell carcinoma is a rare neuroendocrine carcinoma that typically appears in sun‐
exposed areas of the elderly. It has a poor prognosis and with its incidence projected to …

Merkel cell carcinoma—update on diagnosis, management and future perspectives

E Zaggana, MP Konstantinou, GH Krasagakis… - Cancers, 2022 - mdpi.com
Simple Summary Merkel cell carcinoma (MCC) is a highly aggressive skin cancer and the
second cause of skin cancer death after melanoma. MCC is an immunogenic tumor. In …

Merkel cell carcinoma: therapeutic update and emerging therapies

A Villani, G Fabbrocini, C Costa… - Dermatology and …, 2019 - Springer
Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine skin cancer
whose incidence has almost doubled in recent decades. Risk factors for MCC include age> …

Merkel cell carcinoma: updates on staging and management

C Cornejo, CJ Miller - Dermatologic Clinics, 2019 - derm.theclinics.com
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma with a high rate of
metastasis and 5-year overall survival (OS) ranging from 50.6% for patients with local …

How we treat Merkel cell carcinoma: within and beyond current guidelines

SY Park, C Doolittle-Amieva, Y Moshiri, T Akaike… - Future …, 2021 - Taylor & Francis
Merkel cell carcinoma (MCC) is an aggressive skin cancer associated with a high risk of
local recurrence and distant metastasis. Optimal care of this potentially life-threatening …

High somatostatin receptor expression and efficacy of somatostatin analogues in patients with metastatic Merkel cell carcinoma

T Akaike, J Qazi, A Anderson, FS Behnia… - British Journal of …, 2021 - academic.oup.com
Background Merkel cell carcinoma (MCC) is an aggressive, high‐grade, cutaneous
neuroendocrine tumour (NET). Agents blocking programmed death 1/programmed death …

[HTML][HTML] Advancing treatment options for merkel cell carcinoma: A review of tumor-targeted therapies

HM Nammour, K Madrigal, CT Starling… - International journal of …, 2024 - mdpi.com
Although rare, Merkel cell carcinoma (MCC) is a highly aggressive and increasingly
prevalent neuroendocrine cancer of the skin. While current interventions, including surgical …

Updates on Merkel cell carcinoma

DA Emge, AR Cardones - Dermatologic clinics, 2019 - derm.theclinics.com
Merkel cell carcinoma (MCC) is a rare, rapidly progressing, and difficult-to-treat
neuroendocrine tumor of the skin that is associated with high mortality. In the last few …