Low-grade systemic inflammation is a key pathophysiological component of atherosclerotic
cardiovascular disease (CVD), and long-term activation of myeloid cells is thought to be …

Understanding the developmental origins of health and disease is integral to overcome the
global tide of obesity and its metabolic consequences, including atherosclerotic …

The prevalence of obesity is increasing worldwide. Experimental animal studies
demonstrate that maternal obesity during pregnancy directly affects cardiac structure and …

Obesity, hypertension, type 2 diabetes mellitus and dyslipidaemia are highly prevalent
among women of reproductive age and contribute to complications in> 30% of pregnancies …

Pregravid obesity is one of the major risk factors for pregnancy complications such as
gestational diabetes mellitus (GDM) and an increased risk of cardiovascular events in …

Abstract Background/Objectives Obesity in pregnancy has been associated with increased
childhood cardiometabolic risk and reduced life expectancy. The UK UPBEAT multicentre …

Maternal obesity is an important risk factor for obesity, cardiovascular, and metabolic
diseases in the offspring. Studies have shown that it leads to hypothalamic inflammation in …

Obesity incidence has been increasing at an alarming rate, especially in women of
reproductive age. It is estimated that 50% of pregnancies occur in overweight or obese …

Background Early growth, stress, and socioeconomic factors are associated with future risk
of individual chronic diseases. It is uncertain whether they also affect the rate of …

Background Preconception or antenatal lifestyle interventions in women with obesity may
prevent adverse cardiovascular outcomes in the child, including cardiac remodelling. We …