Current management and future challenges in salivary glands cancer

LD Locati, R Ferrarotto, L Licitra, M Benazzo… - Frontiers in …, 2023 - frontiersin.org
Salivary gland cancers (SGCs) are rare, accounting for less than 5% of all malignancies of
the head and neck region, and are morphologically heterogeneous. The diagnosis is mainly …

Molecular factors in carcinoma ex pleomorphic adenoma: systematic review and meta‐analysis

S Key, C Chia, Z Hasan, P Sundaresan… - The …, 2024 - Wiley Online Library
Objective Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignant salivary gland
tumor. Although multiple reviews have been published on salivary gland malignancies, it …

Adenoid cystic carcinoma (AdCC): a clinical survey of a large patient cohort

M Zupancic, A Näsman, A Berglund, T Dalianis… - Cancers, 2023 - mdpi.com
Simple Summary Adenoid cystic carcinoma (AdCC) is a rare heterogenous disease, often
difficult to diagnose and prognosticate and, therefore, also challenging to treat optimally. To …

Adoption of adjuvant chemotherapy in high‐risk salivary gland malignancies

AJ Gordon, MS Chow, A Patel, KS Hu, Z Li… - Head & …, 2023 - Wiley Online Library
Background The present study characterizes national trends in the utilization of adjuvant
chemotherapy to treat salivary gland malignancies. Methods The National Cancer Database …

Systemic therapies for salivary gland carcinomas: An overview of published clinical trials

LC Silva, ME Pérez-de-Oliveira… - … Oral, Patología Oral …, 2023 - pmc.ncbi.nlm.nih.gov
Background There is no consensus about effective systemic therapy for salivary gland
carcinomas (sgcs). Our aim was summarized the clinical trials assessing the systemic …

Targeting human EGFR 2 (HER2) in salivary gland carcinoma

M Wotman, A El-Naggar, R Ferrarotto - Expert review of anticancer …, 2023 - Taylor & Francis
Introduction Human epidermal growth factor receptor 2 (HER2) protein overexpression,
gene amplification, and activating mutations have been identified in a subset of salivary …

Heterogeneous immune landscapes and macrophage dynamics in primary and lung metastatic adenoid cystic carcinoma of the head and neck

X Wang, T Ma, H Liu, S Zhang, G Yang, Y Zhao… - Frontiers in …, 2024 - frontiersin.org
Introduction Recurrent or metastatic adenoid cystic carcinoma (ACC) of the head and neck is
rare and highly aggressive. Due to the ineffectiveness of immune checkpoint therapies, this …

High-grade salivary gland cancer: is surgery followed by radiotherapy an adequate treatment to reach tumor control? Results from a tertiary referral centre focussing …

V Freitag, S Lettmaier, S Semrau, M Hecht… - European Archives of …, 2022 - Springer
Abstract Purpose Salivary Gland cancer (SGC) is a rare and heterogenous group of tumors.
Standard therapeutic options achieve high local but poor distant control rates, especially in …

Combination chemotherapy with taxane and platinum in patients with salivary gland carcinoma: a retrospective study of docetaxel plus cisplatin and paclitaxel plus …

R Onaga, T Enokida, K Ito, Y Ueda, S Okano… - Frontiers in …, 2023 - frontiersin.org
Background Despite advances in precision medicine, most patients with recurrent or
metastatic salivary gland carcinoma still need conventional chemotherapies, such as the …

Efficacy of Cetuximab Combined with Paclitaxel in Patients with Recurrent Salivary Gland Carcinoma: A Retrospective Observational Study

R Sato, R Yuasa, T Kumai, R Wakisaka, H Komatsuda… - ORL, 2024 - karger.com
Introduction: Due to the rarity and various histological types, a standard chemotherapy
regimen for recurrent or metastatic salivary gland carcinoma (SGC) has not been …