The number of publicly available parasitic worm genome sequences has increased
dramatically in the past three years, and research interest in helminth functional genomics is …

Nematodes are abundant and diverse, and include many parasitic species. Molecular
phylogenetic analyses have shown that parasitism of plants and animals has arisen at least …

Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …

Abstract WormBase (www. wormbase. org) is a central repository for research data on the
biology, genetics and genomics of Caenorhabditis elegans and other nematodes. The …

Generating the raw data for a de novo genome assembly project for a target eukaryotic
species is relatively easy. This democratization of access to large-scale data has allowed …

Programmed DNA rearrangements in the single-celled eukaryote Oxytricha trifallax
completely rewire its germline into a somatic nucleus during development. This elaborate …

In most organisms, the whole genome is maintained throughout the life span. However,
exceptions occur in some species where the genome is reduced during development …

In some eukaryotes, germline and somatic genomes differ dramatically in their composition.
Here we characterise a major germline–soma dissimilarity caused by a germline-restricted …

Programmed DNA elimination is a developmentally regulated process leading to the
reproducible loss of specific genomic sequences. DNA elimination occurs in unicellular …

Abstract WormBase (http://www. wormbase. org/) is a highly curated resource dedicated to
supporting research using the model organism Caenorhabditis elegans. With an electronic …