Multifunctional DNA-Collagen Biomaterials: Developmental Advances and Biomedical Applications

N Pipis, BD James, JB Allen - ACS Biomaterials Science & …, 2025 - ACS Publications
The complexation of nucleic acids and collagen forms a platform biomaterial greater than
the sum of its parts. This union of biomacromolecules merges the extracellular matrix …

Exploring the Fibrous Nature of Single-Stranded DNA–Collagen Complexes: Nanostructural Observations and Physicochemical Insights

N Pipis, KA Stewart, M Tabatabaei, LN Williams… - ACS …, 2024 - ACS Publications
Nucleic acid–collagen complexes (NACCs) are a self-assembled biomimetic fibrillary
platform arising from the spontaneous complexation of single-stranded DNA (ssDNA) …

Self-Assembled DNA–Collagen Bioactive Scaffolds Promote Cellular Uptake and Neuronal Differentiation

N Singh, A Singh, D Bhatia - ACS Biomaterials Science & …, 2024 - ACS Publications
Different modalities of DNA/collagen complexes have been utilized primarily for gene
delivery studies. However, very few studies have investigated the potential of these …

An Investigation of PCR Inhibition Using Plexor®‐Based Quantitative PCR and Short Tandem Repeat Amplification

RE Thompson, G Duncan… - Journal of forensic …, 2014 - Wiley Online Library
A common problem in forensic DNA typing is PCR inhibition resulting in allele dropout and
peak imbalance. In this paper, we have utilized the P lexor® real‐time PCR quantification kit …

Mineralized DNA-collagen complex-based biomaterials for bone tissue engineering

BD James, P Guerin, Z Iverson, JB Allen - International journal of biological …, 2020 - Elsevier
DNA is a highly polyanionic biomolecule that complexes with both collagen and
hydroxyapatite. By combining these complexes, we synthesized nucleic-acid collagen …

Electrochemical trans-channel assay for efficient evaluation of tumor cell invasiveness

L Shi, L Wang, X Ma, M Jalalah… - … applied materials & …, 2021 - ACS Publications
Efficiently assessing the invasive capability of tumor cells is critical both for the research and
treatment of cancer. Here, we report a novel method called the electrochemical trans …

Oligomer length defines the self-assembly of single-stranded DNA–collagen complex fibers

BD James, S Saenz, A van Gent… - … Biomaterials Science & …, 2019 - ACS Publications
Collagen and single-stranded DNA (ssDNA) complex to self-assemble into fibers depending
on the length of the ssDNA and the relative amounts of collagen and ssDNA in solution. We …

Insight into a molecular interaction force supporting peptide backbones and its implication to protein loops and folding

QS Du, D Chen, NZ Xie, RB Huang… - Journal of Biomolecular …, 2015 - Taylor & Francis
Although not being classified as the most fundamental protein structural elements like α-
helices and β-strands, the loop segment may play considerable roles for protein stability …