Exploring plant-derived bisindole alkaloids: a comprehensive review of sources, phytochemistry and cytotoxicity

Z Zhang, Y Li, Y Li, X Song, R Wang, D Zhang - Phytochemistry Reviews, 2024 - Springer
Bisindole alkaloids represent a notable class of natural compounds distinguished by their
characteristic bisindole structure and recognized for their anticancer potential. Over the past …

Ethnomedicinal uses, biological activities, and toxicity of Voacanga africana Stapf Ex Scott-Elliot

EO Bekoe, JAA Opare, M Lartey… - Advances in Traditional …, 2024 - Springer
Voacanga africana, is a medicinal plant widely used in many African countries. Various parts
of this plant are used, but more especially the seeds are held in high esteem for it's their …

Efficient Access to the Iboga Skeleton: Optimized Procedure to Obtain Voacangine from Voacanga africana Root Bark

B González, C Fagundez, A Peixoto de Abreu Lima… - ACS …, 2021 - ACS Publications
Iboga alkaloids are a group of monoterpenoid indole alkaloids with promising and intriguing
biological activities. Ibogaine is the representative member of the series and has become …

Monoterpenoid indole alkaloids from the stem barks of Voacanga africana and their chemotaxonomic significance

M Qin, W Gao, H Wang, S Yin, J Hu, W Gao… - … Systematics and Ecology, 2024 - Elsevier
The phytochemical investigation of the stem barks of Voacanga africana resulted in the
isolation of fifteen known monoterpenoid indole alkaloids (1–15). The structures of the …

Virtual screening–molecular docking–activity evaluation of Ailanthus altissima (Mill.) swingle bark in the treatment of ulcerative colitis

S Ma, L Liu, X Li, Y Xie, X Shi, S Wang - BMC Complementary Medicine …, 2023 - Springer
Background The dried bark of Ailanthus altissima (Mill.) Swingle is widely used in traditional
Chinese medicine for the treatment of ulcerative colitis. The objective of this study was to …

[HTML][HTML] Voacanga africana-artesunate and Voacanga africana-amodiaquine combinations as effective anti-plasmodial agents in mice.

DA Frimpong, A Moomin, SA Nkansah, AO Antwi… - Scientific African, 2025 - Elsevier
Background Malaria is a global health problem due to its high incidence of morbidity and
mortality, especially in children and pregnant women. However, the Plasmodium parasite …

[HTML][HTML] In vivo antibacterial activity of the methanol extract of Voacanga africana Stapf (Apocynaceae) stem bark against clinical multidrug-resistant Salmonella …

LA Awah, GS Taïwe, SB Babiaka, F Cho-Ngwa… - Scientific African, 2024 - Elsevier
The emergence of multidrug-resistant (MDR) Salmonella has increased the burden of its
infections. Voacanga africana, used traditionally to treat some bacterial infections, has …

Potent anti-amoebic effects of ibogaine, voacangine and the root bark alkaloid fraction of tabernaemontana arborea

JC Carrero, V Curay-Herrera, L Chacon-Nino… - Planta …, 2023 - thieme-connect.com
Plants of Tabernaemontana species have several pharmacological activities including
antimicrobial effects. Amoebiasis continues to be a public health problem, with increasing …

Editorial to Special Issue—“Structure-Activity Relationships (SAR) of Natural Products”

W Sippl, F Ntie-Kang - Molecules, 2021 - mdpi.com
The topic of structure-activity-relationships (SAR) has recently drawn a lot of attention, and
there is increasing interest in natural products (NPs) as a “source of inspiration” for the …

[PDF][PDF] Scientific African

IO Lawal, MB Olaniyi, SO Rufai, AO Aremu - 2021 - researchgate.net
abstract Persea americana Mill (Lauraceae) is popular medicinal plant used for the
treatment and management of a wide range of diseases. In this study, the foliar …