Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

Galectins are a family of animal lectins that bind β-galactosides. Outside the cell, galectins
bind to cell-surface and extracellular matrix glycans and thereby affect a variety of cellular …

Galectin‐3 is a β‐galactoside‐binding animal lectin of appro‐ximately 30 kDa and is
evolutionarily highly conserved. Galectin‐3 is promiscuous, its localization within the tissue …

Alternative macrophage activation is implicated in diverse disease pathologies such as
asthma, organ fibrosis, and granulomatous diseases, but the mechanisms underlying …

Galectins, β‐galactoside‐binding animal lectins, are differentially expressed by various
immune cells as well as a wide range of other cell types. Extracellularly, galectins are able to …

Inflammation is a critical process for eliminating pathogens, but can lead to serious
deleterious effects if left unchecked. Identifying the endogenous factors that control immune …

Atopic asthma is a chronic inflammatory pulmonary disease characterised by recurrent
episodes of wheezy, laboured breathing with an underlying Th2 cell-mediated inflammatory …

Galectin-3 (Gal3) is one of the most studied members of the galectin family that mediate
various biological processes such as growth regulation, immune function, cancer …

Individuals with chronic asthma show a progressive decline in lung function that is thought to
be due to structural remodeling of the airways characterized by subepithelial fibrosis and …

Airway remodeling is accepted to be a determining component within the natural history of
asthma. It is a phenomenon characterized by changes in the airways structures that marches …