The extracellular matrix (ECM) is synthesized and secreted by embryonic cells beginning at
the earliest stages of development. Our understanding of ECM composition, structure and …

Cells in multicellular organisms are surrounded by a complex three-dimensional
macromolecular extracellular matrix (ECM). This matrix, traditionally thought to serve a …

Cells such as fibroblasts and endothelial cells migrate through the coordinated responses of
discrete integrin-containing focal adhesions and complexes. In contrast, little is known about …

The neural crest serve as an excellent model to better understand mechanisms of embryonic
cell migration. Cell tracing studies have shown that cranial neural crest cells (CNCCs) …

A successful immune response depends on the migration of lymphocytes into lymph nodes
or inflamed tissues where they make contact with antigen‐presenting cells. We are …

Advances in microscale 3D cell culture systems have helped to elucidate cellular
physiology, understand mechanisms of stem cell differentiation, produce pathophysiological …

Connexin 43 knockout (Cx43α1KO) mice have conotruncal heart defects that are associated
with a reduction in the abundance of cardiac neural crest cells (CNCs) targeted to the heart …

Cell migration entails the dynamic redistribution of adhesion receptors from the cell rear
toward the cell front, where they form new protrusions and adhesions. This process may …

Neural crest cells are highly migratory cells that give rise to many derivatives including
peripheral ganglia, craniofacial structures and melanocytes. Neural crest cells migrate along …

The neural crest cells (NCCs), a transient group of cells that emerges from the dorsal aspect
of the neural tube during early vertebrate development has been a fascinating group of cells …