Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

Staphylococcus aureus is an important human pathogen and a leading cause of death
worldwide. Phenol-soluble modulins (PSMs) have recently emerged as a novel toxin family …

In most environments, microorganisms evolve in a sessile mode of growth, designated as
biofilm, which is characterized by cells embedded in a self‐produced extracellular matrix …

Fibrillar protein aggregates are a hallmark of a range of human disorders, from prion
diseases to dementias, but are also encountered in several functional contexts. Yet, the …

The outcome of encounters between Staphylococcus (S.) aureus and its human host ranges
from life-threatening infection through allergic reactions to symptom-free colonization. The …

Staphylococci are abundant bacteria of the human skin microbiome. Several species,
particularly Staphylococcus aureus and Staphylococcus epidermidis, are opportunistic …

Bacterial biofilms represent an essential part of Earth's ecosystem that can cause multiple
ecological, technological, and health problems. The environmental resilience and …

PSMs are a recently discovered family of short, amphipathic, α-helical peptides in
staphylococci. Several PSMs are key virulence determinants, particularly in highly virulent …

Staphylococci are frequently implicated in human infections, and continue to pose a
therapeutic dilemma due to their ability to form deeply seated microbial communities, known …