The third variable region, V3, of the gp120 surface envelope glycoprotein is an
approximately 35-residue-long, frequently glycosylated, highly variable, disulfide-bonded …

Rhesus monkeys were infected with mutant forms of simian immunodeficiency virus lacking
dual combinations of the 4th, 5th and 6th sites for N-linked glycosylation in the external …

A review and discussion of new knowledge on the structure and function of mammalian
alkaline phosphatases (APs) gained over the last 25 years. It covers:* The structure …

We present the results of a preliminary investigation of the efficacy of a therapeutic dendritic
cell (DC)-based vaccine for HIV-1. We immunized 18 chronically HIV-1-infected and …

Nonhuman primate models for the evaluation of HIV-1 preventi... : Current Opinion in HIV and
AIDS Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies …

Laboratory measures of antigen-specific immunity are an essential component of the
vaccine discovery process. For human immunodeficiency virus type 1 (HIV-1), this process …

Drug resistance testing has been shown to be beneficial for clinical management of HIV type
1 infected patients. Whereas phenotypic assays directly measure drug resistance, the …

Transient antiretroviral treatment with tenofovir,(R)-9-(2-phosphonylmethoxypropyl) adenine,
begun shortly after inoculation of rhesus macaques with the highly pathogenic simian …

Live-attenuated strains of simian immunodeficiency virus (SIV) routinely confer apparent
sterilizing immunity against pathogenic SIV challenge in rhesus macaques. Understanding …

Deletion mutants of the pathogenic clone of simian immunodeficiency virus isolate 239
(SIVmac239) were derived that are missing nef, vpr, and upstream sequences (US) in the …