Modeling Heartland virus disease in mice and therapeutic intervention with 4′-fluorouridine

JB Westover, KH Jung, C Alkan, KM Boardman… - Journal of …, 2024 - Am Soc Microbiol
Heartland virus (HRTV) is an emerging tick-borne bandavirus that causes a febrile illness of
varying severity in humans, with cases reported in eastern and midwestern regions of the …

The Effect of Tryptophan-to-Tyrosine Mutation at Position 61 of the Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Virus on Viral Replication …

JY Park, A Senevirathne, KKS Lloren… - International Journal of …, 2024 - mdpi.com
In our prior investigations, we elucidated the role of the tryptophan-to-tyrosine substitution at
the 61st position in the nonstructural protein NSsW61Y in diminishing the interaction …

RECENT ADVANCES IN THE DEVELOPMENT OF SMALL MOLECULE INHIBITORS FOR TARGETING PROTEIN-PROTEIN INTERACTIONS IN DRUG DISCOVERY.

S Narayan, S Rawat, R Ranjan… - … & Cellular Archives, 2023 - search.ebscohost.com
Protein-protein interactions (PPIs) aSre pivotal in biology and present promising therapeutic
opportunities. This review focuses on recent strides in developing small molecule PPI …

Immunogenicity of a vaccine candidate for severe fever with Thrombocytopenia syndrome virus that utilized an attenuated Salmonella delivery system expressing …

JY Park, JH Woon, G Won, JH Lee - 예방수의학회지, 2024 - dbpia.co.kr
Severe Fever with Thrombocytopenia Syndrome (SFTS) is a newly emerging tick-borne
disease caused by the SFTS virus (SFTSV), which belongs to the phlebovirus in the …