Artificial cell membrane systems for biosensing applications

T Osaki, S Takeuchi - Analytical chemistry, 2017 - ACS Publications
Biological membranes provide a physical boundary that separates the inside and outside of
a cell or organelle. They also mediate signal transduction and transport of various molecules …

A microscale soft ionic power source modulates neuronal network activity

Y Zhang, J Riexinger, X Yang, E Mikhailova, Y Jin… - Nature, 2023 - nature.com
Bio-integrated devices need power sources to operate,. Despite widely used technologies
that can provide power to large-scale targets, such as wired energy supplies from batteries …

Physicochemical characteristics of droplet interface bilayers

Y Huang, GG Fuller, VC Suja - Advances in Colloid and Interface Science, 2022 - Elsevier
Droplet interface bilayer (DIB) is a lipid bilayer formed when two lipid monolayer-coated
aqueous droplets are brought in contact within an oil phase. DIBs, especially post …

Orthogonal light-activated DNA for patterned biocomputing within synthetic cells

D Hartmann, R Chowdhry, JM Smith… - Journal of the American …, 2023 - ACS Publications
Cell-free gene expression is a vital research tool to study biological systems in defined
minimal environments and has promising applications in biotechnology. Developing …

Membrane protein-based biosensors

N Misawa, T Osaki, S Takeuchi - Journal of the Royal …, 2018 - royalsocietypublishing.org
This review highlights recent development of biosensors that use the functions of membrane
proteins. Membrane proteins are essential components of biological membranes and have a …

Multi-compartment encapsulation of communicating droplets and droplet networks in hydrogel as a model for artificial cells

M Bayoumi, H Bayley, G Maglia, KT Sapra - Scientific reports, 2017 - nature.com
Constructing a cell mimic is a major challenge posed by synthetic biologists. Efforts to this
end have been primarily focused on lipid-and polymer-encapsulated containers, liposomes …

Functional aqueous droplet networks

MJ Booth, VR Schild, FG Downs, H Bayley - Molecular BioSystems, 2017 - pubs.rsc.org
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …

Light-patterning of synthetic tissues with single droplet resolution

MJ Booth, V Restrepo Schild, SJ Box, H Bayley - Scientific reports, 2017 - nature.com
Synthetic tissues can be generated by forming networks of aqueous droplets in lipid-
containing oil. Each droplet contains a cell-free expression system and is connected to its …

Bilayer networks within a hydrogel shell: a robust chassis for artificial cells and a platform for membrane studies

DK Baxani, AJL Morgan, WD Jamieson… - Angewandte Chemie …, 2016 - Wiley Online Library
The ability to make artificial lipid bilayers compatible with a wide range of environments, and
with sufficient structural rigidity for manual handling, would open up a wealth of opportunities …

Inherently UV photodegradable poly (methacrylate) gels

JM Scheiger, S Li, M Brehm, A Bartschat… - Advanced Functional …, 2021 - Wiley Online Library
Organogels (hydrophobic polymer gels) are soft materials based on polymeric networks
swollen in organic solvents. They are hydrophobic and possess a high content of solvent …