The role of systemic inflammation in cancer‐associated muscle wasting and rationale for exercise as a therapeutic intervention

CL Cole, IR Kleckner, A Jatoi, EM Schwarz… - JCSM clinical …, 2018 - Wiley Online Library
Progressive skeletal muscle wasting in cancer cachexia involves a process of dysregulated
protein synthesis and breakdown. This catabolism may be the result of mal‐nutrition, and an …

Contribution of adrenergic mechanisms for the stress‐induced breast cancer carcinogenesis

D Silva, C Quintas, J Gonçalves… - Journal of Cellular …, 2022 - Wiley Online Library
Breast cancer is the most common and deadliest type of cancer in women. Stress exposure
has been associated with carcinogenesis and the stress released neurotransmitters …

Adherence to mediterranean diet and nutritional status in women with breast cancer: What is their impact on disease progression and recurrence-free patients' survival …

M Mantzorou, M Tolia, A Poultsidi, GK Vasios… - Current …, 2022 - mdpi.com
Introduction: Nutritional status impacts the survival of patients with cancer. There are few
studies that investigate the role of nutritional status on breast cancer survival in women with …

Tumor-derived MMPs regulate cachexia in a Drosophila cancer model

W Lodge, M Zavortink, S Golenkina, F Froldi, C Dark… - Developmental Cell, 2021 - cell.com
Cachexia, the wasting syndrome commonly observed in advanced cancer patients,
accounts for up to one-third of cancer-related mortalities. We have established a Drosophila …

Prognostic significance of the skeletal muscle index and systemic inflammatory index in patients with lymph node-positive breast cancer after radical mastectomy

R Tang, JP Deng, L Zhang, WW Zhang, JY Sun, F Chi… - BMC cancer, 2022 - Springer
Background The role of skeletal muscle index (SMI) and systemic inflammation index (SII)
for patients with lymph node-positive breast cancer remain controversial. This retrospective …

Metastasis and cachexia: alongside in clinics, but not so in animal models

R Tomasin, ACBM Martin… - Journal of cachexia …, 2019 - Wiley Online Library
Cancer cachexia is a paraneoplastic syndrome characterized by lean mass wasting (with or
without fat mass decrease), culminating in involuntary weight loss, which is the key clinical …

IL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia

GG Eskiler, G Güney Eskiler, E Bezdegumeli, Z Ozman… - 2019 - acikerisim.sakarya.edu.tr
IL-6 mediated JAK/STAT3 signaling pathway in cancer patients with cachexia Page 1 Indexed
and abstracted in Science Citation Index Expanded and in Journal Citation Reports/Science …

Chemotherapy‐induced loss of bone and muscle mass in a mouse model of breast cancer bone metastases and cachexia

BA Hain, H Xu, JR Wilcox, D Mutua… - JCSM Rapid …, 2019 - Wiley Online Library
Background Chemotherapy used to treat malignancy can lead to loss of skeletal muscle
mass and reduced force production, and can reduce bone volume in mice. We have shown …

Updates on the pathogenesis of advanced lung cancer‐induced cachexia

R Zhu, Z Liu, R Jiao, C Zhang, Q Yu, S Han… - Thoracic …, 2019 - Wiley Online Library
Advanced lung cancer is becoming a chronic disease threatening human life and health.
Cachexia has been recognized as the most common problem associated with advanced …

Metabolic changes during cancer cachexia pathogenesis

N Shyh-Chang - Translational research in breast cancer: biomarker …, 2017 - Springer
Wasting of adipose tissue and skeletal muscle is a hallmark of metastatic cancer and a
major cause of death. Like patients with cachexia caused by other chronic infections or …