Utilizing epigenetics to study the shared nature of development and biological aging across the lifespan

L Raffington - npj Science of Learning, 2024 - nature.com
Recently, biological aging has been quantified in DNA-methylation samples of older adults
and applied as so-called “methylation profile scores”(MPSs) in separate target samples …

Educational mobility, pace of aging, and lifespan among participants in the Framingham heart study

GHJ Graf, AE Aiello, A Caspi, M Kothari, H Liu… - JAMA Network …, 2024 - jamanetwork.com
Importance People who complete more education live longer lives with better health. New
evidence suggests that these benefits operate through a slowed pace of biological aging. If …

New Directions in Geroscience: Integrating Social and Behavioral Drivers of Biological Aging

L Nielsen, AL Marsland, EJ Hamlat… - Psychosomatic …, 2024 - journals.lww.com
The “geroscience hypothesis” posits that slowing the physiological processes of aging
would lead to delayed disease onset and longer healthspan and lifespan. This shift from a …

The Effect of Education, Income, and Access to Health Services on the Quality of Life of the Elderly in West Java

J Utomo, AY Rukmana… - … Science Social and …, 2023 - wsj.westscience-press.com
This research explores the dynamic interplay between education, income, access to health
services, and the quality of life among the elderly in West Java. Utilizing a sample of 120 …

Consequences of heterogeneity in aging: parental age at death predicts midlife all-cause mortality and hospitalization in a Swedish national birth cohort

A Thalén, A Ledberg - BMC geriatrics, 2024 - Springer
Background The processes that underlie aging may advance at different rates in different
individuals and an advanced biological age, relative to the chronological age, is associated …

Aging, Race, and Health Disparities: Recommendations From the Research Centers Collaborative Network

S Jain, GS Bey, SN Forrester… - The Journals of …, 2024 - academic.oup.com
Racial disparities in adverse health outcomes with aging have been well described. Yet,
much of the research focuses on racial comparisons, with relatively less attention to the …

Educational Mobility, the Pace of Biological Aging, and Lifespan in the Framingham Heart Study

G Graf, AE Aiello, A Caspi, M Kothari, H Liu, TE Moffitt… - medRxiv, 2023 - medrxiv.org
Importance: People who complete more education live longer lives with better health. New
evidence suggests that these benefits operate through a slowed pace of biological aging. If …

[HTML][HTML] Linked emergence of racial disparities in mental health and epigenetic biological aging across childhood and adolescence

M Aikins, Y Willems, C Mitchell, B Goosby, L Raffington - bioRxiv, 2024 - ncbi.nlm.nih.gov
Marginalization due to structural racism may confer an increased risk for aging-related
diseases–in part–via effects on people's mental health. Here we leverage a prospective birth …

Dissecting Alzheimer's Disease Risk in Asian American Elders: A Classification and Regression Tree Approach

SS Moon, L Anderson, J Liu, J Lee… - Journal of Alzheimer's …, 2024 - content.iospress.com
Background: Alzheimer's disease (AD) poses a growing public health challenge, particularly
with an aging population. While extensive research has explored the relationships between …

Poverty Status at Birth Predicts Epigenetic Changes at Age 15

S Assari, H Zare - Journal of Biomedical and Life Sciences, 2024 - scipublications.com
We used 15 years of follow up of 854 racially and ethnically diverse birth cohort who were
followed from birth to age 15. Structural equation modeling (SEM) was used to examine the …