Glycosylation in cancer: mechanisms and clinical implications

SS Pinho, CA Reis - Nature Reviews Cancer, 2015 - nature.com
Despite recent progress in understanding the cancer genome, there is still a relative delay in
understanding the full aspects of the glycome and glycoproteome of cancer. Glycobiology …

Blood groups in infection and host susceptibility

L Cooling - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Blood group antigens represent polymorphic traits inherited among individuals and
populations. At present, there are 34 recognized human blood groups and hundreds of …

Helicobacter pylori and Gastric Cancer: Factors That Modulate Disease Risk

LE Wroblewski, RM Peek Jr… - Clinical microbiology …, 2010 - Am Soc Microbiol
Helicobacter pylori is a gastric pathogen that colonizes approximately 50% of the world's
population. Infection with H. pylori causes chronic inflammation and significantly increases …

The role of O-glycosylation in human disease

A Magalhães, HO Duarte, CA Reis - Molecular Aspects of Medicine, 2021 - Elsevier
O-glycosylation is a highly frequent post-translation modification of proteins, with important
functional implications in both physiological and disease contexts. The biosynthesis of O …

Bacterial adhesins in host-microbe interactions

KA Kline, S Fälker, S Dahlberg, S Normark… - Cell host & …, 2009 - cell.com
Most commensal and pathogenic bacteria interacting with eukaryotic hosts express
adhesive molecules on their surfaces that promote interaction with host cell receptors or with …

[HTML][HTML] Infection with Helicobacter pylori

IARC Working Group on the Evaluation of … - … , liver flukes and …, 1994 - ncbi.nlm.nih.gov
The presence of spiral-shaped bacteria on human gastric mucosa was first recognized
nearly one hundred years ago (Pel, 1899). These bacteria were isolated for the first time in …

Virulence of Helicobacter pylori outer membrane proteins: an updated review

C Xu, DM Soyfoo, Y Wu, S Xu - European Journal of Clinical Microbiology …, 2020 - Springer
Helicobacter pylori (H. pylori) infection is associated with some gastric diseases, such as
gastritis, peptic ulcer, and gastric cancer. CagA and VacA are known virulence factors of H …

Helicobacter pylori diversity and gastric cancer risk

TL Cover - MBio, 2016 - Am Soc Microbiol
Gastric cancer is a leading cause of cancer-related death worldwide. Helicobacter pylori
infection is the strongest known risk factor for this malignancy. An important goal is to identify …

An Overview of Helicobacter pylori Infection

R FitzGerald, SM Smith - Helicobacter pylori, 2021 - Springer
Helicobacter pylori (H. pylori) represents one of the most widespread bacterial infections
globally. Infection causes chronic gastritis and increases the risk of peptic ulcer disease …

The Role of Helicobacter pylori Outer Membrane Proteins in Adherence and Pathogenesis

M Oleastro, A Ménard - Biology, 2013 - mdpi.com
Helicobacter pylori is one of the most successful human pathogens, which colonizes the
mucus layer of the gastric epithelium of more than 50% of the world's population. This …