The scientific interest in the beneficial properties of natural substances has been recognized
for decades, as well as the growing attention in extracellular vesicles (EVs) released by …

Diabetes is one of the most frequent diseases throughout the world and its incidence is
predicted to exponentially progress in the future. This metabolic disorder is associated with …

Abstract Background Approximately 20–50% of patients presenting with localized colorectal
cancer progress to stage IV metastatic disease (mCRC) following initial treatment and this is …

Radiotherapy and internal radioisotope therapy (brachytherapy) induce tumor cell death
through different molecular signaling pathways. However, these therapies in cancer patients …

This study investigated the effects of pentoxifylline (PTX), high intensity interval training
(HIIT) and moderate intensity continuous training (MICT) separately and in combination, on …

Immunotherapy utilizing tumor-infiltrating lymphocytes (TILs) is a promising approach for
cancer treatment. Pentoxifylline (PTXF), a xanthine derivative, exhibits antitumor properties …

Fungal keratitis (FK) is a blinding ocular disease, which mainly results from fungal damage
and excessive inflammation. Pentoxifylline, a kind of methylxanthine, has been discovered …

Inhalation of high concentrations of phosgene often causes pulmonary edema, which
obstructs the airway and causes tissue hypoxia. There is currently no specific antidote. This …

Background Prostate cancer is one of the most frequently diagnosed types of cancers
worldwide. In its initial period, the tumor is hormone-sensitive, but in advanced states, it …

Cyclophosphamide (CP) is one of the chemotherapeutic drugs, which plays its role by
interfering with all rapidly proliferating tissues like cancer and testis. The aim of this study …