Solute carrier transporters (SLCs) are a class of important transmembrane proteins that are
involved in the transportation of diverse solute ions and small molecules into cells. There are …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous
system (CNS). Its homeostasis is maintained by neuronal and glial GABA transporters …

The presynaptic serotonin transporter (SERT) clears extracellular serotonin following
vesicular release to ensure temporal and spatial regulation of serotonergic signalling and …

The serotonin transporter (SERT) tightly regulates synaptic serotonin levels and has been
the primary target of antidepressants. Binding of inhibitors to the allosteric site of human …

Serotonin is an essential mediator regulating diverse neural processes, and its deregulation
is related to the development of debilitating neurological diseases. In particular, the human …

Neurotransmitter: sodium symporters (NSSs) play critical roles in neural signaling by
regulating neurotransmitter uptake into cells powered by sodium electrochemical gradients …

Membrane transporters of the solute carrier 6 (SLC6) family mediate various physiological
processes by facilitating the translocation of amino acids, neurotransmitters, and other …

The serotonin transporter (SERT) is a member of the Solute Carrier 6 (SLC6) family and is
responsible for maintaining the appropriate level of serotonin in the brain. Dysfunction of …

In chordates, energy buffering is achieved in part through phosphocreatine, which requires
cellular uptake of creatine by the membrane‐embedded creatine transporter …

Methylenedioxymethamphetamine (MDMA,'ecstasy') is re‐emerging in clinical settings as a
candidate for the treatment of specific neuropsychiatric disorders (eg post‐traumatic stress …