Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

Body-based biomolecular sensing systems, including wearable, implantable and
consumable sensors allow comprehensive health-related monitoring. Glucose sensors have …

Optical biosensors are frontrunners for the rapid and real-time detection of analytes,
particularly for low concentrations. Among them, whispering gallery mode (WGM) resonators …

The eukaryotic cell is compartmentalized into subcellular niches, including membrane-
bound and membrane-less organelles. Proteins localize to these niches to fulfil their …

Since the discovery of antibiotics in the first quarter of the twentieth century, their use has
been the principal approach to treat bacterial infection. Modernized medicine such as …

Nanomedicines, while having been approved for cancer therapy, present many challenges
such as low stability, rapid clearance, and nonspecificity leading to off-target toxicity …

Several ubiquitin chain types have remained unstudied, mainly because tools and
techniques to detect these posttranslational modifications are scarce. Linkage-specific …

The concept of engineering robust protein scaffolds for novel binding functions emerged 20
years ago, one decade after the advent of recombinant antibody technology. Early examples …

Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

Introduction The importance of biomarkers for pharmaceutical drug development and clinical
diagnostics is more significant than ever in the current shift toward personalized medicine …