Increased awareness of autoimmune encephalitis has led to two unintended consequences:
a high frequency of misdiagnoses and the inappropriate use of diagnostic criteria for …

Tauopathies are a heterogeneous group of neurodegenerative disorders that are
characterised by the aggregation of the microtubule-associated protein tau into filamentous …

Sepsis-associated encephalopathy (SAE) is a severe and frequent complication of sepsis
causing delirium, coma, and long-term cognitive dysfunction. We identified microglia and …

Background and Objectives The clinical criteria for autoimmune encephalitis (AE) were
proposed by Graus et al. in 2016. In this study, the AE criteria were validated in the real …

Paraneoplastic neurological syndromes (PNS) include any symptomatic and non-metastatic
neurological manifestations associated with a neoplasm. PNS associated with antibodies …

Anti-IgLON5 disease is a rare neurological, probably autoimmune, disorder associated in
many cases with a specific tauopathy. Only a few post-mortem neuropathological studies …

Background Anti-IgLON5 disease is a rare neurological disorder characterized by
autoantibodies against IgLON5, and pathological evidence of neurodegeneration. IgLON5 is …

Paralleling advances with respect to more common antibody-mediated encephalitides, such
as anti-N-methyl-D-aspartate receptor (NMDAR) and anti-leucine-rich glioma-inactivated 1 …

Background In 2014, we first described novel autoantibodies to the inositol 1, 4, 5-
trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar …

Objective Serum neurofilament light chain (sNfL) is a biomarker for neuroaxonal damage
and has been found to be elevated in several neurological diseases with neuronal …