[HTML][HTML] Female obesity and infertility: outcomes and regulatory guidance

S Marinelli, G Napoletano, M Straccamore… - Acta Bio Medica …, 2022 - ncbi.nlm.nih.gov
Obesity has been associated with reduced fertility, although the dynamics and mechanisms
which link excess weight to reduced fertility are not yet fully clarified. Obese women …

Cost‐effectiveness analysis of individual‐level obesity treatment in paediatrics: A scoping review

A Dhillon, M Mayer, L Kysh, DS Fox… - Pediatric …, 2024 - Wiley Online Library
Objectives This scoping review informs a health economics perspective on the treatment of
paediatric obesity. The results detail recently published research findings on the cost …

Lipid-lowering strategies for primary prevention of coronary heart disease in the UK: a cost-effectiveness analysis

JI Morton, C Marquina, M Lloyd, GF Watts… - …, 2024 - Springer
Aim We aimed to assess the cost effectiveness of four different lipid-lowering strategies for
primary prevention of coronary heart disease initiated at ages 30, 40, 50, and 60 years from …

Integrating the biology of cardiovascular disease into the epidemiology of economic decision modelling via Mendelian randomisation

Z Ademi, JI Morton, D Liew, SJ Nicholls, S Zoungas… - …, 2022 - Springer
Health economic analyses are essential for health services research, providing decision-
makers and payers with evidence about the value of interventions relative to their …

Quantifying the causal impact of biological risk factors on healthcare costs

J Lee, S Jukarainen, A Karvanen, P Dixon… - Nature …, 2023 - nature.com
Understanding the causal impact that clinical risk factors have on healthcare-related costs is
critical to evaluate healthcare interventions. Here, we used a genetically-informed design …

Causal estimation of long-term intervention cost-effectiveness using genetic instrumental variables: an application to cancer

P Dixon, RM Martin, S Harrison - Medical Decision Making, 2024 - journals.sagepub.com
Background This article demonstrates a means of assessing long-term intervention cost-
effectiveness in the absence of data from randomized controlled trials and without recourse …

Cost-effectiveness of smoking cessation interventions in patients with ischemic stroke and transient ischemic attack

PM Wechsler, AL Liberman, D Restifo, EL Abramson… - Stroke, 2023 - Am Heart Assoc
Background: Smoking cessation rates after stroke and transient ischemic attack are
suboptimal, and smoking cessation interventions are underutilized. We performed a cost …

Integrated Analyses of Single-Cell Transcriptome and Mendelian Randomization Reveal the Protective Role of Resistin in Sepsis Survival in Intensive Care Unit

H Chen, H Luo, T Tian, S Li, Y Jiang - International Journal of Molecular …, 2023 - mdpi.com
The high morbidity and mortality rates associated with sepsis highlight the challenges of
finding specific remedies for this condition in the intensive care unit (ICU). This study aimed …

Holistic modelling as a catalyst for effective obesity policy

J McLaughlin, CS Rejon, M Bell, B Schwander… - bmj, 2024 - bmj.com
Holistic modelling as a catalyst for effective obesity policy Page 1 Holistic modelling as a
catalyst for effective obesity policy Reducing the prevalence of obesity requires multifaceted …

Systematic comparison of Mendelian randomisation studies and randomised controlled trials using electronic databases

MK Sobczyk, J Zheng, GD Smith, TR Gaunt - BMJ open, 2023 - bmjopen.bmj.com
Objective To scope the potential for (semi)-automated triangulation of Mendelian
randomisation (MR) and randomised controlled trials (RCTs) evidence since the two …