[HTML][HTML] Acute kidney injury

JA Kellum, P Romagnani, G Ashuntantang… - Nature reviews Disease …, 2021 - nature.com
Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part
of a range of conditions summarized as acute kidney diseases and disorders (AKD), in …

[HTML][HTML] The Hippo pathway and its correlation with acute kidney injury

C Zhang, CL Li, KX Xu, ZH Zheng, GZ Cheng… - Zoological …, 2022 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a significant clinical complication with a substantial impact on
morbidity and mortality, for which therapeutic options remain limited. The Hippo signaling …

Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway

T Wang, Z Chen, H Chen, X Yu, L Wang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Brucea javanica (L.) Merr. is a medicinal herb used in
China for the prevention and treatment of diseases such as cancer and malaria. Brusatol …

Single cell dissection of epithelial-immune cellular interplay in acute kidney injury microenvironment

M Zhang, L Wu, Y Deng, F Peng, T Wang… - Frontiers in …, 2022 - frontiersin.org
Background Understanding the acute kidney injury (AKI) microenvironment changes and the
complex cellular interaction is essential to elucidate the mechanisms and develop new …

HOOK1 Inhibits the Progression of Renal Cell Carcinoma via TGF‐β and TNFSF13B/VEGF‐A Axis

L Yin, W Li, X Chen, R Wang, T Zhang… - Advanced …, 2023 - Wiley Online Library
Accumulating evidence shows HOOK1 disordered in human malignancies. However, the
clinicopathological and biological significance of HOOK1 in renal cell carcinoma (RCC) …

Vascular heterogeneity of tight junction Claudins guides organotropic metastasis

X Zhou, VS LeBleu, E Fletcher-Sananikone, J Kim… - Nature Cancer, 2024 - nature.com
Carcinomas are associated with metastasis to specific organs while sparing others. Breast
cancer presents with lung metastasis but rarely kidney metastasis. Using this difference as …

Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer

X Zhou, P Kurywchak, K Wolf-Dennen, SPY Che… - … Therapy Methods & …, 2021 - cell.com
Bladder cancer (BC), a heterogeneous disease characterized by high recurrence rates, is
diagnosed and monitored by cystoscopy. Accurate clinical staging based on biopsy remains …

The novel m6A writer METTL5 as prognostic biomarker probably associating with the regulation of immune microenvironment in kidney cancer

W Zhang, Y Chen, Z Zeng, Y Peng, L Li, N Hu, X Gao… - Heliyon, 2022 - cell.com
Nowadays, among all urinary system cancers, the mortality of kidney cancer (KC) has risen
to the first, and the incidence has been keeping on the third. Many recent studies have …

[HTML][HTML] Astaxanthin suppresses the metastasis of clear cell renal cell carcinoma through ROS scavenging

J Gong, S Jiang, Y Huang, D Yang, L Zhang, Z Li… - Journal of Functional …, 2024 - Elsevier
Clear cell renal cell carcinoma (ccRCC) represents a prevalent form of kidney cancer, and
its poor prognosis is closely tied to the occurrence of metastasis. ROS can drive epithelial …

Expression pattern of cancer-associated cellular senescence genes in clear cell renal cell carcinoma distinguishes tumor subclasses with clinical implications

Z Zhu, Q Cao, J Chen, Y Sun, F Liu, J Li, M Tan - Scientific Reports, 2025 - nature.com
Clear cell renal cell carcinoma (ccRCC) is a highly lethal subtype of renal cancer.
Accumulating evidence suggests cellular senescence impacts tumor development and …