Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin
D receptor and 1α-hydroxylase. In vitro studies have shown that 1, 25-dihydroxyvitamin D …

The SARS-CoV-2 virus responsible for the COVID-19 pandemic has generated an explosion
of interest both in the mechanisms of infection leading to dissemination and expression of …

Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

The encounter between Mycobacterium tuberculosis (Mtb) and the host leads to a complex
and multifaceted immune response possibly resulting in latent infection, tubercular disease …

Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …

Recent findings point toward diet having a major impact on human health. Diets can either
affect the gut microbiota resulting in alterations in the host's physiological responses or by …

Autophagy is well equipped functionally to isolate microbial pathogens in autophagosomes
and to carry out their clearance by dismemberment in the course of catabolic processes in …

The pleiotropic role of vitamin D has been explored over the past decades and there is
compelling evidence for an epidemiological association between poor vitamin D status and …

Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms that can
cause chronic pulmonary infection, particularly in individuals with pre-existing inflammatory …

Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …