The Impact of NO2 on Epithelial Barrier Integrity of a Primary Cell‐Based Air–Liquid Interface Model of the Nasal Respiratory Epithelium
H Moratin, J Lang, MS Picker, A Rossi… - Journal of Applied …, 2024 - Wiley Online Library
Nitrogen dioxide (NO2) is a pervasive gaseous air pollutant with well‐documented
hazardous effects on health, necessitating precise toxicological characterization. While prior …
hazardous effects on health, necessitating precise toxicological characterization. While prior …
[HTML][HTML] Transcriptomic Analysis of Air–Liquid Interface Culture in Human Lung Organoids Reveals Regulators of Epithelial Differentiation
To develop in vitro respiratory models, it is crucial to identify the factors involved in epithelial
cell differentiation. In this study, we comprehensively analyzed the effects of air–liquid …
cell differentiation. In this study, we comprehensively analyzed the effects of air–liquid …
Small molecule-directed differentiation of submerged-cultured human nasal airway epithelia for respiratory disease modelling
HHM Dreyer, GN Ithakisiou, S Spelier, MK Iwanski… - bioRxiv, 2024 - biorxiv.org
Submerged cultures of undifferentiated or transformed epithelial cells are widely used in
respiratory research due to their ease of use and scalability. However, these systems fail to …
respiratory research due to their ease of use and scalability. However, these systems fail to …
Effect of hypoxia on Cystic Fibrosis Transmembrane conductance Regulator channel corrected by Elexacaftor/Tezacaftor/Ivacaftor
K Pascarel, J Colas, T Carrez, C Barrault… - Medical Research …, 2024 - hal-ciheam.iamm.fr
The accumulation of mucus resulting from the obstruction of bronchi of cystic fibrosis (CF)
patients, induces a reduction of the oxygen (O2) pressure and produces a hypoxic …
patients, induces a reduction of the oxygen (O2) pressure and produces a hypoxic …