Genetic basis for congenital heart disease: revisited: a scientific statement from the American Heart Association

ME Pierpont, M Brueckner, WK Chung, V Garg… - Circulation, 2018 - Am Heart Assoc
This review provides an updated summary of the state of our knowledge of the genetic
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …

Cardiovascular complications of down syndrome: scoping review and expert consensus

K Dimopoulos, A Constantine, P Clift, R Condliffe… - Circulation, 2023 - Am Heart Assoc
Cardiovascular disease is a leading cause of morbidity and mortality in individuals with
Down syndrome. Congenital heart disease is the most common cardiovascular condition in …

Atypical aging in Down syndrome

WB Zigman - Developmental disabilities research reviews, 2013 - Wiley Online Library
At present, there may be over 210,000 people with Down syndrome (DS) over the age of 55
in the United States (US) who have significant needs for augmented services due to …

Co‐occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines

GT Capone, B Chicoine, P Bulova… - American Journal of …, 2018 - Wiley Online Library
Adults with Down syndrome (DS) represent a unique population who are in need of clinical
guidelines to address their medical care. The United States Preventive Service Task Force …

[HTML][HTML] Genetics of congenital heart disease: a narrative review of recent advances and clinical implications

J Yasuhara, V Garg - Translational Pediatrics, 2021 - ncbi.nlm.nih.gov
Congenital heart disease (CHD) is the most common human birth defect and remains a
leading cause of mortality in childhood. Although advances in clinical management have …

Advances in the understanding of the genetic determinants of congenital heart disease and their impact on clinical outcomes

MW Russell, WK Chung, JR Kaltman… - Journal of the American …, 2018 - Am Heart Assoc
Congenital heart defects (CHDs) are the most common type of birth defect occurring in% 1%
of live births1 and, if minor cardiac abnormalities such as bicuspid aortic valve are included …

Cardiovascular disease in Down syndrome

P Versacci, D Di Carlo, MC Digilio… - Current opinion in …, 2018 - journals.lww.com
Cardiovascular disease in Down syndrome : Current Opinion in Pediatrics Cardiovascular
disease in Down syndrome : Current Opinion in Pediatrics Log in or Register Subscribe to …

[HTML][HTML] Contemporary outcomes of complete atrioventricular septal defect repair: analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database

JDS Louis, U Jodhka, JP Jacobs, X He, KD Hill… - The Journal of thoracic …, 2014 - Elsevier
Objective Contemporary outcomes data for complete atrioventricular septal defect (CAVSD)
repair are limited. We sought to describe early outcomes of CAVSD repair across a large …

Down syndrome and congenital heart disease: perioperative planning and management

DR Delany, SS Gaydos, DA Romeo… - Journal of Congenital …, 2021 - Springer
Approximately 50% of newborns with Down syndrome have congenital heart disease. Non-
cardiac comorbidities may also be present. Many of the principles and strategies of …

Refining the Society of Thoracic Surgeons Congenital Heart Surgery Database mortality risk model with enhanced risk adjustment for chromosomal abnormalities …

JP Jacobs, SM O'Brien, KD Hill, SR Kumar… - The Annals of thoracic …, 2019 - Elsevier
Background The Society of Thoracic Surgeons Congenital Heart Surgery Database Mortality
Risk Model adjusts not only for procedure and age group pairings but also for additional …