Metals and mechanisms of carcinogenesis

QY Chen, T DesMarais, M Costa - Annual review of …, 2019 - annualreviews.org
Metal exposure is pervasive and not limited to sporadic poisoning events or toxic waste
sites. Hundreds of millions of people around the globe are affected by chronic metal …

Environmental factors in cardiovascular disease

KE Cosselman, A Navas-Acien… - Nature Reviews …, 2015 - nature.com
Environmental exposure is an important but underappreciated risk factor contributing to the
development and severity of cardiovascular disease (CVD). The heart and vascular system …

Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence

A Ruiz-Hernandez, CC Kuo, P Rentero-Garrido… - Clinical …, 2015 - Springer
Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

Increased global placental DNA methylation levels are associated with gestational diabetes

C Reichetzeder, SE Dwi Putra, T Pfab, T Slowinski… - Clinical …, 2016 - Springer
Background Gestational diabetes mellitus (GDM) is associated with adverse pregnancy
outcomes. It is known that GDM is associated with an altered placental function and changes …

Response of transposable elements to environmental stressors

IR Miousse, MCG Chalbot, A Lumen… - … Research/Reviews in …, 2015 - Elsevier
Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …

Toenails as a biomarker of exposure to arsenic: A review

AJ Signes-Pastor, E Gutiérrez-González… - Environmental …, 2021 - Elsevier
This systematic review summarizes the current evidence related to the reliability of toenail
total arsenic concentrations (thereafter “arsenic”) as a biomarker of long-term exposure …

Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

SM Tajuddin, DG Hernandez, BH Chen… - Clinical …, 2019 - Springer
Abstract Background African Americans (AAs) experience premature chronic health
outcomes and longevity disparities consistent with an accelerated aging phenotype. DNA …

Select early-life environmental exposures and DNA methylation in the placenta

M Mortillo, CJ Marsit - Current environmental health reports, 2023 - Springer
Abstract Purpose of Review To summarize recent literature relating early-life environmental
exposures on DNA methylation in the placenta, to identify how variation in placental …

The Impact of External Factors on the Epigenome: In Utero and over Lifetime

EG Toraño, MG García… - BioMed research …, 2016 - Wiley Online Library
Epigenetic marks change during fetal development, adult life, and aging. Some changes
play an important role in the establishment and regulation of gene programs, but others …

Pancreatic cancer risk in relation to lifetime smoking patterns, tobacco type, and dose–response relationships

E Molina-Montes, L Van Hoogstraten… - … , biomarkers & prevention, 2020 - AACR
Background: Despite smoking being a well-established risk factor for pancreatic cancer,
there is a need to further characterize pancreatic cancer risk according to lifespan smoking …