Members of the Flaviviridae virus family comprise a large group of enveloped viruses with a
single-strand RNA genome of positive polarity. Several genera belong to this family …

The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …

Abstract The BioGRID (Biological General Repository for Interaction Datasets, thebiogrid.
org) is an open‐access database resource that houses manually curated protein and …

Dengue and Zika viral infections affect millions of people annually and can be complicated
by hemorrhage and shock or neurological manifestations, respectively. However, a thorough …

Advances in nuclease-based gene-editing technologies have enabled precise, stable, and
systematic genetic engineering of glycosylation capacities in mammalian cells, opening up a …

The Flavivirus genus contains many important human pathogens, including dengue,
Japanese encephalitis (JE), tick-borne encephalitis (TBE), West Nile (WN), yellow fever (YF) …

Dengue virus (DENV) infections cause the most prevalent mosquito-borne viral disease
worldwide, for which no therapies are available. DENV encodes seven non-structural (NS) …

Flaviviruses, including dengue virus (DENV) and Zika virus (ZIKV), cause severe human
disease. Co-opting cellular factors for viral translation and viral genome replication at the …

Viruses are obligate intracellular pathogens that are dependent on cellular machineries for
their replication. Recent technological breakthroughs have facilitated reliable identification …

Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat
to human health. Flaviviruses replicate in compartmentalized replication organelles derived …