Structural insights into nuclear transcription by eukaryotic DNA-dependent RNA polymerases
The eukaryotic transcription apparatus synthesizes a staggering diversity of RNA molecules.
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
The labour of nuclear gene transcription is, therefore, divided among multiple DNA …
Conservation between the RNA polymerase I, II, and III transcription initiation machineries
A Vannini, P Cramer - Molecular cell, 2012 - cell.com
Recent studies of the three eukaryotic transcription machineries revealed that all initiation
complexes share a conserved core. This core consists of the RNA polymerase (I, II, or III), the …
complexes share a conserved core. This core consists of the RNA polymerase (I, II, or III), the …
Structural insights into preinitiation complex assembly on core promoters
INTRODUCTION RNA polymerase II (Pol II)–mediated transcription initiation requires
assembly of a preinitiation complex (PIC), during which the 14-subunit transcription factor IID …
assembly of a preinitiation complex (PIC), during which the 14-subunit transcription factor IID …
Recruitment of RNA polymerase III to its target promoters
L Schramm, N Hernandez - Genes & development, 2002 - genesdev.cshlp.org
A key step in retrieving the information stored in the complex genomes of eukaryotes
involves the identification of transcription units and, more specifically, the recognition of …
involves the identification of transcription units and, more specifically, the recognition of …
Molecular genetics of the RNA polymerase II general transcriptional machinery
M Hampsey - Microbiology and Molecular Biology Reviews, 1998 - Am Soc Microbiol
Transcription initiation by RNA polymerase II (RNA pol II) requires interaction between cis-
acting promoter elements and trans-acting factors. The eukaryotic promoter consists of core …
acting promoter elements and trans-acting factors. The eukaryotic promoter consists of core …
Survey and summary transcription by RNA polymerases I and III
MR Paule, RJ White - Nucleic acids research, 2000 - academic.oup.com
The task of transcribing nuclear genes is shared between three RNA polymerases in
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
eukaryotes: RNA polymerase (pol) I synthesises the large rRNA, pol II synthesises mRNA …
A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast
We report genetic and biochemical evidence that the RNA polymerase II carboxy-terminal
domain (CTD) lnteracts with a large multlsubunit complex that contains TATA-binding …
domain (CTD) lnteracts with a large multlsubunit complex that contains TATA-binding …
Crystal structure of a TFIIB–TBP–TATA-element ternary complex
DB Nikolov, H Chen, ED Halay, AA Usheva, K Hisatake… - Nature, 1995 - nature.com
The crystal structure of the transcription factorIIB (TFIIB)/TATA box-binding protein
(TBP)/TATA-element ternary complex is described at 2.7 Å resolution. Core TFIIB resembles …
(TBP)/TATA-element ternary complex is described at 2.7 Å resolution. Core TFIIB resembles …
[HTML][HTML] Facilitated recycling pathway for RNA polymerase III
G Dieci, A Sentenac - Cell, 1996 - cell.com
We show that the high in vitro transcription efficiency of yeast RNA pol III is mainly due to
rapid recycling. Kinetic analysis shows that RNA polymerase recycling on preassembled …
rapid recycling. Kinetic analysis shows that RNA polymerase recycling on preassembled …
Control of gene expression through regulation of the TATA-binding protein
BF Pugh - Gene, 2000 - Elsevier
The assembly of transcription complexes at eukaryotic promoters involves a number of
distinct steps including chromatin remodeling, and recruitment of a TATA-binding protein …
distinct steps including chromatin remodeling, and recruitment of a TATA-binding protein …