Controversies in ocular myasthenia gravis

A Evoli, R Iorio - Frontiers in Neurology, 2020 - frontiersin.org
Myasthenia gravis (MG) with symptoms limited to eye muscles [ocular MG (OMG)] is a rare
disease. OMG incidence varies according to ethnicity and age of onset. In recent years, both …

Ocular myasthenia gravis: A current overview

R Behbehani - Eye and Brain, 2023 - Taylor & Francis
Ocular myasthenia gravis (OMG) is a neuromuscular disease characterized by autoantibody
production against post-synaptic proteins in the neuromuscular junction. The …

Prediction of generalization of ocular myasthenia gravis under immunosuppressive therapy in Northwest China

J Ding, S Zhao, K Ren, D Dang, H Li, F Wu, M Zhang… - BMC neurology, 2020 - Springer
Background It is well demonstrated that immunosuppressants can reduce, but not eliminate
the risk of generalized development in ocular myasthenia gravis (OMG). In this study, we …

Development and validation of a nomogram for predicting generalization in patients with ocular myasthenia gravis

Z Ruan, C Sun, Y Lang, F Gao, R Guo, Q Xu… - Frontiers in …, 2022 - frontiersin.org
Background This study aims to develop and validate a nomogram for predicting 1-and 2-
year generalization probabilities in patients with ocular myasthenia gravis (OMG). Methods …

[HTML][HTML] Myasthenia gravis: MuSK MG, late-onset MG and ocular MG

F Deymeer - Acta Myologica, 2020 - ncbi.nlm.nih.gov
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction which
affects all striated muscles, resulting in fluctuating weakness. Approaching MG as a disease …

Update on ocular myasthenia gravis

M O'Hare, C Doughty - Seminars in Neurology, 2019 - thieme-connect.com
Myasthenia gravis is an antibody-mediated autoimmune disorder of the post-synaptic
neuromuscular junction resulting in fluctuating, fatigable weakness. Most patients first …

Effect of immunosuppression in risk of developing generalized symptoms in ocular myasthenia gravis: A retrospective cohort study

D Menon, M Alharbi, HD Katzberg, V Bril, MG Mendoza… - Neurology, 2024 - neurology.org
Backgrounds and Objectives Early use of immunosuppression has been suggested to
prevent generalization of ocular myasthenia gravis (OMG), but high-quality evidence is …

Risk factors for generalization in patients with ocular myasthenia gravis: a multicenter retrospective cohort study

RJ Guo, T Gao, Z Ruan, HY Zhou, F Gao, Q Xu… - Neurology and …, 2022 - Springer
Introduction Many patients with ocular myasthenia gravis (OMG) progress to generalized
disease within the first 2 years of the onset of ocular symptoms. Several retrospective studies …

Association of immunosuppression treatment with generalization among patients with ocular myasthenia gravis: A propensity score analysis

Z Ruan, R Guo, H Zhou, F Gao, Y Lin… - European Journal of …, 2022 - Wiley Online Library
Background To analyze disease generalization in patients with ocular myasthenia gravis
(OMG) treated with immunosuppression compared with patients without …

Ocular myasthenia gravis: updates on an elusive target

AT Melson, CM McClelland, MS Lee - Current Opinion in …, 2020 - journals.lww.com
Our understanding of OMG and its variable phenotypes continues to evolve. Autoantibody
testing increasingly provides valuable diagnostic and prognostic information. Despite these …