The Continuing Threat of Methicillin-Resistant Staphylococcus aureus

M Gajdács - Antibiotics, 2019 - mdpi.com
Staphylococcus aureus has been an exceptionally successful pathogen, which is still
relevant in modern age-medicine due to its adaptability and tenacity. This bacterium may be …

From oxiranes to oligomers: Architectures of US FDA approved pharmaceuticals containing oxygen heterocycles

MD Delost, DT Smith, BJ Anderson… - Journal of Medicinal …, 2018 - ACS Publications
Oxygen heterocycles are the second most common type of heterocycles that appear as
structural components of US Food and Drug Administration (FDA) approved …

[HTML][HTML] Peripheral intravenous catheter failure: A secondary analysis of risks from 11,830 catheters

N Marsh, EN Larsen, M Takashima, T Kleidon… - International journal of …, 2021 - Elsevier
Background Peripheral intravenous catheters are an essential medical device which are
prone to complications and failure. Objectives Identify patient, provider and device risk …

Tackling antibiotic resistance with compounds of natural origin: A comprehensive review

FJ Álvarez-Martínez, E Barrajón-Catalán, V Micol - Biomedicines, 2020 - mdpi.com
Drug-resistant bacteria pose a serious threat to human health worldwide. Current antibiotics
are losing efficacy and new antimicrobial agents are urgently needed. Living organisms are …

Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides

X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Diagnostic accuracy of procalcitonin, neutrophil-lymphocyte count ratio, C-reactive protein, and lactate in patients with suspected bacterial sepsis

L Ljungström, AK Pernestig, G Jacobsson… - PloS one, 2017 - journals.plos.org
Background Early recognition is a key factor to achieve improved outcomes for septic
patients. Combinations of biomarkers, as opposed to single ones, may improve timely …

Evaluation of wound healing efficiency of vancomycin-loaded electrospun chitosan/poly ethylene oxide nanofibers in full thickness wound model of rat

F Kalalinia, Z Taherzadeh, N Jirofti, N Amiri… - International journal of …, 2021 - Elsevier
Electrospun hybrid nanofibers have been extensively regarded as drug carriers. This study
tries to introduce a nano fibrous wound dressing as a new strategy for a topical drug-delivery …

Antibacterial and antibiofilm potential of silver nanoparticles against antibiotic-sensitive and multidrug-resistant Pseudomonas aeruginosa strains

D de Lacerda Coriolano, JB de Souza… - Brazilian Journal of …, 2021 - Springer
Due to the severity of infections caused by P. aeruginosa and the limitations in treatment, it is
necessary to find new therapeutic alternatives. Thus, the use of silver nanoparticles (AgNPs) …

Expansion of chemical space for natural products by uncommon P450 reactions

X Zhang, S Li - Natural product reports, 2017 - pubs.rsc.org
Covering: 2000 to 2017 Cytochrome P450 enzymes (P450s) are the most versatile
biocatalysts in nature. The catalytic competence of these extraordinary hemoproteins is …

Multilayered nanofibrous scaffold of Polyvinyl alcohol/gelatin/poly (lactic-co-glycolic acid) enriched with hemostatic/antibacterial agents for rapid acute hemostatic …

G Pandey, P Pandey, DK Arya, S Kanaujiya… - International journal of …, 2023 - Elsevier
Electrospun nanofibers scaffolds show promising potential in wound healing applications.
This work aims to fabricate nanofibrous wound dressing as a novel approach for a topical …